Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

Abstract NAT10-catalyzed N4-acetylcytidine (ac4C) has emerged as a vital post-
transcriptional modulator on the coding transcriptome by promoting mRNA stability …

RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

Silicosis is a serious silica-induced respiratory disease for which there is currently no
effective treatment. Irreversible pulmonary fibrosis caused by persistent inflammation is the …

Abstract Global Developmental Delay/Intellectual disability (ID) is the term used to describe
various disorders caused by abnormal brain development and characterized by impairments …

Abstract tRNA is one of the most conserved and abundant RNA species, which plays a key
role during protein translation. tRNA molecules are post-transcriptionally modified by tRNA …

Background Accumulating studies suggested that posttranscriptional modifications exert a
vital role in the tumorigenesis of diffuse large B‐cell lymphoma (DLBCL). N4‐acetylcytidine …

Oligodendrocytes are specialized cells that confer neuronal myelination in the central
nervous system. Leukodystrophies associated with oligodendrocyte deficits and …