A review on diverse heterocyclic compounds as the privileged scaffolds in non-steroidal aromatase inhibitors
Breast cancer, emerging malignancy is common among women due to overexpression of
estrogen. Estrogens are biosynthesized from androgens by aromatase, a cytochrome P450 …
estrogen. Estrogens are biosynthesized from androgens by aromatase, a cytochrome P450 …
Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs
Aromatase is an enzyme that plays a crucial role in the biosynthesis of estrogens, which are
hormones that contribute to the growth of certain types of breast cancer. In particular …
hormones that contribute to the growth of certain types of breast cancer. In particular …
Synthesis, structure-activity relationships and molecular docking studies of phenyldiazenyl sulfonamides as aromatase inhibitors
L Giampietro, M Gallorini, N Gambacorta… - European Journal of …, 2021 - Elsevier
The exploration of innovative aromatase inhibitors represents an important approach for the
identification of new therapeutic treatments of breast cancer. In this respect, a series of …
identification of new therapeutic treatments of breast cancer. In this respect, a series of …
Design, synthesis, in vitro and in silico studies of some novel triazoles as anticancer agents for breast cancer
Against the increasing incidence of breast cancer in postmenopausal women in recent
years, a few clinically approved inhibitors and their side-effect profiles indicate the need for …
years, a few clinically approved inhibitors and their side-effect profiles indicate the need for …
Phosphonium salts and P-ylides
This review collects and describes the literature published between January and December
2019 focusing on the preparation, characterisation and applications of phosphonium salts …
2019 focusing on the preparation, characterisation and applications of phosphonium salts …
Tertiary phosphines: preparation and reactivity
EI Musina, AS Balueva, AA Karasik - 2021 - books.rsc.org
This chapter covers the literature published during 2019 relating to the synthesis and the
reactivity of tertiary phosphines, but excluding the chemistry of their metal complexes …
reactivity of tertiary phosphines, but excluding the chemistry of their metal complexes …