The continual supply of ATP to the fundamental cellular processes that underpin skeletal
muscle contraction during exercise is essential for sports performance in events lasting …

Key points Ketone bodies are proposed to represent an alternative fuel source driving
energy production, particularly during exercise. Biologically, the extent to which …

Rapid oscillations in cytosolic calcium (Ca2 þ) coordinate muscle contraction, relaxation,
and physical movement. Intriguingly, dietary nitrate decreases ATP cost of contraction …

Skeletal muscle disuse reduces muscle protein synthesis rates and induces atrophy, events
associated with decreased mitochondrial respiration and increased reactive oxygen …

Purpose With the development of radiation metabolomics, a large number of radiation-
related metabolic biomarkers have been identified and validated. The L-carnitine and …

Key points Blood flow restricted resistance exercise (BFR‐RE) is capable of inducing
comparable adaptations to traditional resistance exercise (RE), despite a lower total …

Fuel interactions in contracting muscle represent a complex interplay between enzymes
regulating carbohydrate and fatty acid catabolism, converging in the mitochondrial matrix …

Intramyocellular lipid (IMCL) utilization is impaired in older individuals, and IMCL
accumulation is associated with insulin resistance. We hypothesized that increasing muscle …

Reductions in mitochondrial function have been proposed to cause insulin resistance,
however the possibility that impairments in insulin signaling negatively affects mitochondrial …

High‐fat diet (HFD) and exercise remodel skeletal muscle mitochondria. The electron
transfer flavoproteins (ETF) transfer reducing equivalents from β‐oxidation into the electron …