FLIM as a promising tool for cancer diagnosis and treatment monitoring

Y Ouyang, Y Liu, ZM Wang, Z Liu, M Wu - Nano-Micro Letters, 2021 - Springer
Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …

Emulsion techniques for the production of pharmacological nanoparticles

R Jenjob, T Phakkeeree, F Seidi… - Macromolecular …, 2019 - Wiley Online Library
Nanoparticles have the advantages over micron‐sized particles to typically provide higher
intracellular uptake and drug bioavailability. Emulsion techniques are commonly used …

Optical methods for non-invasive determination of skin penetration: current trends, advances, possibilities, prospects, and translation into in vivo human studies

ME Darvin - Pharmaceutics, 2023 - mdpi.com
Information on the penetration depth, pathways, metabolization, storage of vehicles, active
pharmaceutical ingredients (APIs), and functional cosmetic ingredients (FCIs) of topically …

Degradation of drug delivery nanocarriers and payload release: A review of physical methods for tracing nanocarrier biological fate

PM Perrigue, RA Murray, A Mielcarek, A Henschke… - Pharmaceutics, 2021 - mdpi.com
Nanoformulations offer multiple advantages over conventional drug delivery, enhancing
solubility, biocompatibility, and bioavailability of drugs. Nanocarriers can be engineered with …

Reflecting size differences of exosomes by using the combination of membrane-targeting viscosity probe and fluorescence lifetime imaging microscopy

N Li, Z Huang, X Zhang, X Song, Y Xiao - Analytical chemistry, 2019 - ACS Publications
Exosomes are cell-secreted membrane-coated vesicles with their sizes variable from 30 to
150 nm. So far, there is no simple, fast, and economical way to evaluate the sizes of …

TAM-preferential nanoparticles intracellularly self-assembled for enhanced macrophage repolarization and cancer immunotherapy

J Li, YF Ding, Z Wang, Q Cheng, J Wei, Z Yang… - Nano Today, 2024 - Elsevier
Immunomodulatory therapy by re-educating M2-like tumor-associated macrophage (TAM) is
often clinically impeded due to the lack of a coordinated platform to sustainably restrain the …

Mechanistic insights into the release of doxorubicin from graphene oxide in cancer cells

E Quagliarini, R Di Santo, D Pozzi, P Tentori… - Nanomaterials, 2020 - mdpi.com
Liposomal doxorubicin (L-DOX) is a popular drug formulation for the treatment of several
cancer types (eg, recurrent ovarian cancer, metastatic breast cancer, multiple myeloma …

Assessing the efficiency of triangular gold nanoparticles as NIR photothermal agents in vitro and melanoma tumor model

S Suarasan, A Campu, A Vulpoi, M Banciu… - International Journal of …, 2022 - mdpi.com
Photothermal therapy (PTT) is gaining a lot of interest as a cancer treatment option with
minimal side effects due to the efficient photothermal agents employed. They are based on …

Casting light on intracellular tracking of a new functional graphene-based microrna delivery system by FLIM and raman imaging

A Piperno, A Mazzaglia, A Scala… - … applied materials & …, 2019 - ACS Publications
The theranostic ability of a new fluorescently labeled cationic cyclodextrin–graphene
nanoplatform (GCD@ Ada-Rhod) was investigated by studying its intracellular trafficking …

[HTML][HTML] Multiphoton imaging of melanoma 3D models with plasmonic nanocapsules

P Zamora-Perez, C Xiao, M Sanles-Sobrido… - Acta Biomaterialia, 2022 - Elsevier
Here, we synthesized plasmonic nanocapsules and studied their induced cellular responses
in 3D melanoma models for their perspective use as a photothermal therapeutic agent. The …