The cornea is the most densely innervated and sensitive tissue in the body. The cornea is
exclusively innervated by C-and A-delta fibers, including mechano-nociceptors that are …

Musculoskeletal pain disorders are the second largest contributor to global disability
underlining the significance of effective treatments. However, treating chronic …

The major Food and Drug Association–approved osteoinductive factors in wide clinical use
are bone morphogenetic proteins (BMPs). Although BMPs can promote robust bone …

The proinflammatory cytokines tumor necrosis factor‐α (TNF‐α) and interleukin‐6 (IL‐6) not
only promote and maintain inflammation, they also contribute to the generation and …

The amygdala has been proposed to serve as a neural center for the modulation of pain
perception. Numerous anatomical and behavioral studies demonstrate that exogenous …

Achilles Tendinopathy is a complex problem, with the most common conservative treatment
being eccentric exercises. Despite multiple studies assessing this treatment regime little is …

Immune-Mediated Inflammatory Diseases (IMIDs) is a descriptive term coined for an eclectic
group of diseases or conditions that share common inflammatory pathways, and for which …

Key points Muscle fibre cross sectional area is enhanced with massage in the form of cyclic
compressive loading during regrowth after atrophy. Massage enhances protein synthesis of …

After peripheral nerve damage macrophages infiltrate the dorsal root ganglia (DRG) in
which cell bodies of lesioned neurons are located. However, infiltration of macrophages into …

Background 6-Shogaol is one of the major compounds in the ginger rhizome that may
contribute to its anti-inflammatory properties. Confirmation of this contribution was sought in …