JC polyomavirus (JCPyV) was the first of now 12 PyVs detected in humans, when in 1964,
PyV particles were revealed by electron microscopy in progressive multifocal …

Progress in stem cell research has revolutionized the medical field for more than two
decades. More recently, the discovery of induced pluripotent stem cells (iPSCs) has allowed …

Genetic variation is a primary determinant of phenotypic diversity. In laboratory mice, genetic
variation can be a serious experimental confounder, and thus minimized through …

ABSTRACT JC polyomavirus (JCPyV) establishes a lifelong persistence in roughly half the
human population worldwide. The cells and tissues that harbor persistent virus in vivo are …

JC polyomavirus (JCPyV) is a human-specific polyomavirus that establishes a silent lifelong
infection in multiple peripheral organs, predominantly those of the urinary tract, of …

JC polyomavirus (JCPyV) is a neuroinvasive pathogen causing a fatal, demyelinating
disease of the central nervous system (CNS) known as progressive multifocal …

Enteroviruses can frequently target the human central nervous system to induce a variety of
neurological diseases. Although enteroviruses are highly cytolytic, emerging evidence has …

ABSTRACT JC polyomavirus (JCPyV) infects 50 to 80% of the population and is the
causative agent of a fatal demyelinating disease of the central nervous system (CNS) …

JC virus (JCV), as an archetype, establishes a lifelong latent or persistent infection in many
healthy individuals. In immunocompromised patients, prototype JCV with variable mutations …

Recently, 11 new human polyomaviruses (HPyVs) have been isolated and named KI, WU,
Merkel cell polyomavirus (MCPyV), HPyV6,− 7,− 9,− 10 and− 12, Trichodysplasia spinulosa …