The human JC polyomavirus (JCPyV): virological background and clinical implications
HH Hirsch, P Kardas, D Kranz, C Leboeuf - Apmis, 2013 - Wiley Online Library
JC polyomavirus (JCPyV) was the first of now 12 PyVs detected in humans, when in 1964,
PyV particles were revealed by electron microscopy in progressive multifocal …
PyV particles were revealed by electron microscopy in progressive multifocal …
[HTML][HTML] iPSC-derived three-dimensional brain organoid models and neurotropic viral infections
M Swingler, M Donadoni, A Bellizzi, S Cakir… - Journal of …, 2023 - Springer
Progress in stem cell research has revolutionized the medical field for more than two
decades. More recently, the discovery of induced pluripotent stem cells (iPSCs) has allowed …
decades. More recently, the discovery of induced pluripotent stem cells (iPSCs) has allowed …
[HTML][HTML] Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic …
L Kaczmarczyk, N Reichenbach, N Blank, M Jonson… - Scientific reports, 2021 - nature.com
Genetic variation is a primary determinant of phenotypic diversity. In laboratory mice, genetic
variation can be a serious experimental confounder, and thus minimized through …
variation can be a serious experimental confounder, and thus minimized through …
Susceptibility of primary human choroid plexus epithelial cells and meningeal cells to infection by JC virus
BA O'Hara, GV Gee, WJ Atwood, SA Haley - Journal of Virology, 2018 - Am Soc Microbiol
ABSTRACT JC polyomavirus (JCPyV) establishes a lifelong persistence in roughly half the
human population worldwide. The cells and tissues that harbor persistent virus in vivo are …
human population worldwide. The cells and tissues that harbor persistent virus in vivo are …
[HTML][HTML] Polyomavirus wakes up and chooses neurovirulence
AB Butic, SA Spencer, SK Shaheen, AE Lukacher - Viruses, 2023 - mdpi.com
JC polyomavirus (JCPyV) is a human-specific polyomavirus that establishes a silent lifelong
infection in multiple peripheral organs, predominantly those of the urinary tract, of …
infection in multiple peripheral organs, predominantly those of the urinary tract, of …
[HTML][HTML] The MAPK/ERK pathway and the role of DUSP1 in JCPyV infection of primary astrocytes
MP Wilczek, FJ Armstrong, RP Geohegan… - Viruses, 2021 - mdpi.com
JC polyomavirus (JCPyV) is a neuroinvasive pathogen causing a fatal, demyelinating
disease of the central nervous system (CNS) known as progressive multifocal …
disease of the central nervous system (CNS) known as progressive multifocal …
Human astrocytic cells support persistent coxsackievirus B3 infection
Enteroviruses can frequently target the human central nervous system to induce a variety of
neurological diseases. Although enteroviruses are highly cytolytic, emerging evidence has …
neurological diseases. Although enteroviruses are highly cytolytic, emerging evidence has …
JC polyomavirus infection reveals delayed progression of the infectious cycle in normal human astrocytes
MP Wilczek, JK DuShane, FJ Armstrong… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT JC polyomavirus (JCPyV) infects 50 to 80% of the population and is the
causative agent of a fatal demyelinating disease of the central nervous system (CNS) …
causative agent of a fatal demyelinating disease of the central nervous system (CNS) …
[HTML][HTML] Database and statistical analyses of transcription factor binding sites in the non-coding control region of JC virus
K Nakamichi, T Shimokawa - Viruses, 2021 - mdpi.com
JC virus (JCV), as an archetype, establishes a lifelong latent or persistent infection in many
healthy individuals. In immunocompromised patients, prototype JCV with variable mutations …
healthy individuals. In immunocompromised patients, prototype JCV with variable mutations …
Early and late promoters of BK polyomavirus, Merkel cell polyomavirus, Trichodysplasia spinulosa-associated polyomavirus and human polyomavirus 12 are among …
U Moens, M Van Ghelue… - Journal of General …, 2015 - microbiologyresearch.org
Recently, 11 new human polyomaviruses (HPyVs) have been isolated and named KI, WU,
Merkel cell polyomavirus (MCPyV), HPyV6,− 7,− 9,− 10 and− 12, Trichodysplasia spinulosa …
Merkel cell polyomavirus (MCPyV), HPyV6,− 7,− 9,− 10 and− 12, Trichodysplasia spinulosa …