Abstract The Julia‐Kocienski (J‐K) olefination is a modified version of Julia‐Lythgoe
olefination. In this reaction, an aldehyde or ketone is coupled with heterocycle‐bearing …

Catalytic asymmetric cyanation reactions of aldehydes and ketones provide efficient routes
for the synthesis of optically active cyanohydrins, which are versatile synthons for the …

Covering: up to 2019 Selective synthesis with control of remote stereogenic centers has long
been a challenge in organic chemistry. In recent years the interest in this topic has been …

The modular synthesis of 1, 3-polyols using a chiral phosphine oxide building block is
reported. This versatile building block works in a repetitive way for the stereocontrolled …

1, 5-Polyol structures present challenges in stereocontrol, configurational assignment, and
diastereomer separation; these are all compromised by remote stereochemical …

An organocatalytic method for the asymmetric synthesis of syn-1, 3-dioxanes as protected 1,
3-diols via dynamic kinetic resolution of in situ generated chiral cyanohydrins has been …

The transition metal-mediated dimerisation of terminal alkynes is an attractive and atom-
economic method for preparing conjugated 1, 3-enynes. Using a phosphine-based …

Longstanding paradigmatic studies have noted anti-1, 3-diastereocontrol in Mukaiyama
aldol reactions with β-silyloxy-and β-alkoxyaldehydes. In our efforts to exploit this …

A pot-economical approach to advanced polyol subunits is reported. The key reactions
involved are iterative use of a phosphate tether-mediated one-pot sequential RCM/CM/H2 …

Diverse classes of natural products contain chiral 1, 5-polyols, within which may be
stereochemical triads of 1, 5, 9-and 1, 5, 7-triols. Biological activities associated with …