Trans‐splicing

EL Lasda, T Blumenthal - Wiley Interdisciplinary Reviews: RNA, 2011 - Wiley Online Library
Trans‐splicing is the joining together of portions of two separate pre‐mRNA molecules. The
two distinct categories of spliceosomal trans‐splicing are genic trans‐splicing, which joins …

Evolutionary insights into RNA trans-splicing in vertebrates

Q Lei, C Li, Z Zuo, C Huang, H Cheng… - Genome biology and …, 2016 - academic.oup.com
Pre-RNA splicing is an essential step in generating mature mRNA. RNA trans-splicing
combines two separate pre-mRNA molecules to form a chimeric non-co-linear RNA, which …

Operons in C. elegans: polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions

J Spieth, G Brooke, S Kuersten, K Lea, T Blumenthal - Cell, 1993 - cell.com
The mRNAs of six C. elegans genes are known to be trans-spliced to SL2. We report here
that a similarly oriented gene is located 100-300 bp upstream of each. We present evidence …

Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles

J Wang, B Czech, A Crunk, A Wallace… - Genome …, 2011 - genome.cshlp.org
Eukaryotic cells express several classes of small RNAs that regulate gene expression and
ensure genome maintenance. Endogenous siRNAs (endo-siRNAs) and Piwi-interacting …

The concerted evolution of 5S ribosomal genes linked to the repeat units of other multigene families.

G Drouin, MM De Sa - Molecular Biology and Evolution, 1995 - academic.oup.com
We review all instances in which the nuclear 5S rRNA genes of fungi, protist, nematode, and
arthropod species have been reported to be linked to the tandemly repeated units of the …

Assays to Detect β-Tubulin Codon 200 Polymorphism in Trichuris trichiura and Ascaris lumbricoides

A Diawara, LJ Drake, RR Suswillo… - PLoS neglected …, 2009 - journals.plos.org
Background The soil-transmitted helminths (STH) Ascaris lumbricoides and Trichuris
trichiura are gastrointestinal parasites causing many disabilities to humans, particularly …

A spliced leader is present on a subset of mRNAs from the human parasite Schistosoma mansoni.

A Rajkovic, RE Davis, JN Simonsen… - Proceedings of the …, 1990 - National Acad Sciences
We present evidence that a subset of mRNAs in the human parasitic trematode Schistosoma
mansoni contain an identical 36-nucleotide spliced leader (SL) sequence at their 5'termini …

TRANS-SPLICING OF NEMATODE PREMESSENGER RNA

TW Nilsen - Annual review of microbiology, 1993 - annualreviews.org
Intermolecular trans-splicing is, by definition, an RNA processing reaction that precisely
joins exons derived from separately transcribed RNAs. In one specific type of trans-splicing …

Nematode spliced leaders—ubiquity, evolution and utility

M Blaxter, L Liu - International journal for parasitology, 1996 - Elsevier
Blaxter M. & Liu L. 1996. Nematode spliced leaders—ubiquity, evolution and utility.
International Journal for Parasitology 26: 1025–1033. Most nematode messenger RNAs …

Transient expression of DNA and RNA in parasitic helminths by using particle bombardment

RE Davis, A Parra, PT LoVerde… - Proceedings of the …, 1999 - National Acad Sciences
Parasitic helminths (worms belonging to several metazoan phyla) cause considerable
morbidity and mortality in humans. They are an important veterinary problem, and they result …