Zebrafish as an animal model for biomedical research
Zebrafish have several advantages compared to other vertebrate models used in modeling
human diseases, particularly for large-scale genetic mutant and therapeutic compound …
human diseases, particularly for large-scale genetic mutant and therapeutic compound …
Little fish, big data: zebrafish as a model for cardiovascular and metabolic disease
The burden of cardiovascular and metabolic diseases worldwide is staggering. The
emergence of systems approaches in biology promises new therapies, faster and cheaper …
emergence of systems approaches in biology promises new therapies, faster and cheaper …
[HTML][HTML] A new perspective on lipid research in age-related macular degeneration
EM van Leeuwen, E Emri, BMJ Merle, JM Colijn… - Progress in retinal and …, 2018 - Elsevier
There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …
Zebrafish embryonic lipidomic analysis reveals that the yolk cell is metabolically active in processing lipid
The role of lipids in providing energy and structural cellular components during vertebrate
development is poorly understood. To elucidate these roles further, we visualized lipid …
development is poorly understood. To elucidate these roles further, we visualized lipid …
Epigenetics in teleost fish: From molecular mechanisms to physiological phenotypes
While the field of epigenetics is increasingly recognized to contribute to the emergence of
phenotypes in mammalian research models across different developmental and …
phenotypes in mammalian research models across different developmental and …
The zebrafish as a model for gastrointestinal tract–microbe interactions
EM Flores, AT Nguyen, MA Odem… - Cellular …, 2020 - Wiley Online Library
The zebrafish (Danio rerio) has become a widely used vertebrate model for bacterial, fungal,
viral, and protozoan infections. Due to its genetic tractability, large clutch sizes, ease of …
viral, and protozoan infections. Due to its genetic tractability, large clutch sizes, ease of …
Inside the β cell: molecular stress response pathways in diabetes pathogenesis
The pathogeneses of the 2 major forms of diabetes, type 1 and type 2, differ with respect to
their major molecular insults (loss of immune tolerance and onset of tissue insulin …
their major molecular insults (loss of immune tolerance and onset of tissue insulin …
Zebrafish: An emerging model system to study liver diseases and related drug discovery
S Katoch, V Patial - Journal of applied toxicology, 2021 - Wiley Online Library
The zebrafish has emerged as a powerful vertebrate model for studying liver‐associated
disorders. Liver damage is a crucial problem in the process of drug development and …
disorders. Liver damage is a crucial problem in the process of drug development and …
Integrative physiology: at the crossroads of nutrition, microbiota, animal physiology, and human health
Nutrition is paramount in shaping all aspects of animal biology. In addition, the influence of
the intestinal microbiota on physiology is now widely recognized. Given that diet also …
the intestinal microbiota on physiology is now widely recognized. Given that diet also …
[PDF][PDF] Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science
A Dubey - Journal of Pharmaceutical Negative Results, 2022 - pnrjournal.com
This is a good thing because animals show other organisms how to stay healthy in their
environment. Biologists can learn more about a lot ofdifferent biological processes by …
environment. Biologists can learn more about a lot ofdifferent biological processes by …