CD44 as a tumor biomarker and therapeutic target
H Xu, M Niu, X Yuan, K Wu, A Liu - Experimental hematology & oncology, 2020 - Springer
CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
Exploring cellular biochemistry with nanobodies
RW Cheloha, TJ Harmand, C Wijne… - Journal of Biological …, 2020 - ASBMB
Reagents that bind tightly and specifically to biomolecules of interest remain essential in the
exploration of biology and in their ultimate application to medicine. Besides ligands for …
exploration of biology and in their ultimate application to medicine. Besides ligands for …
Single Domain Antibodies Targeting Receptor Binding Pockets of NadA Restrain Adhesion of Neisseria meningitidis to Human Brain Microvascular Endothelial Cells
A Kulkarni, E Mochnáčová, P Majerova… - Frontiers in molecular …, 2020 - frontiersin.org
Neisseria adhesin A (NadA), one of the surface adhesins of Neisseria meningitides (NM),
interacts with several cell types including human brain microvascular endothelial cells …
interacts with several cell types including human brain microvascular endothelial cells …
Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: overcoming the antigen challenge and enabling discovery strategies
R Dodd, DJ Schofield, T Wilkinson, ZT Britton - Methods, 2020 - Elsevier
Complex integral membrane proteins, which are embedded in the cell surface lipid bilayer
by multiple transmembrane spanning helices, encompass families of proteins which are …
by multiple transmembrane spanning helices, encompass families of proteins which are …
Engineering Nanobody Targeting Cancer Stem Cells
Nanobodies (Nbs) are great molecular tools that can circumvent the limitations of traditional
antibodies such as large size, low stability, slow clearance, and high immunogenicity …
antibodies such as large size, low stability, slow clearance, and high immunogenicity …
In Silico Investigation of Signal Peptide Sequences to Enhance Secretion of CD44 Nanobodies Expressed in Escherichia coli
S Kavousipour, S Mohammadi… - Current …, 2021 - ingentaconnect.com
Background: The selection of a suitable signal peptide that can direct recombinant proteins
from the cytoplasm to the extracellular space is an important criterion affecting the …
from the cytoplasm to the extracellular space is an important criterion affecting the …
Maximizing Diversity and Functionality in Human Single-Domain Antibody Phage Display Libraries
OM Gomez - 2023 - orbit.dtu.dk
Antibodies are essential proteins of our immune system, playing a critical role in defending
our bodies against various diseases. These proteins, also known as immunoglobulins …
our bodies against various diseases. These proteins, also known as immunoglobulins …
Screening of tumor-targeting peptides for diagnosis and therapy through phage display technology
Z Song, Y Zhang, Y Zhu, M Zhang, X Liu… - Blood&Genomics, 2021 - blood-genomics.com
Phage display technology was introduced by G. Smith in 1985, which is highly effective in
the selection of affinity peptides from a library containing billions of display peptides. The …
the selection of affinity peptides from a library containing billions of display peptides. The …
[PDF][PDF] https://www. jbc. org/cgi/doi/10.1074/jbc. REV120. 012960 The latest version is at
RW Cheloha, TJ Harmand, C Wijne, TU Schwartz… - researchgate.net
Reagents that bind tightly and specifically to biomolecules of interest remain essential in the
exploration of biology and in their ultimate application to medicine. Besides ligands for …
exploration of biology and in their ultimate application to medicine. Besides ligands for …