Is polysialylated NCAM not only a regulator during brain development but also during the formation of other organs?

CE Galuska, T Lütteke, SP Galuska - Biology, 2017 - mdpi.com
In mammals several cell adhesion molecules are involved during the pre-and postnatal
development of all organ systems. A very prominent member of this family is the neural cell …

[HTML][HTML] Membrane oligo-and polysialic acids

T Janas, T Janas - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2011 - Elsevier
Polysialic acid (polySia) and oligosialic acid (oligoSia) chains are linear polysaccharides
composed of sialic acid monomers. The majority of biological poly/oligoSia chains are …

Polysialic acid is present in mammalian semen as a post-translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII

P Simon, S Bäumner, O Busch, R Röhrich… - Journal of Biological …, 2013 - ASBMB
Fertilization in animals is a complex sequence of several biochemical events beginning with
the insemination into the female reproductive tract and, finally, leading to embryogenesis …

Polysialic acid modulates only the antimicrobial properties of distinct histones

K Zlatina, SP Galuska - Acs Omega, 2019 - ACS Publications
Histones are not only the organizing and regulatory elements of the genome, the five
histones—H1, H2A, H2B, H3, and H4—also fulfill many tasks outside the cell. Their release …

Determination of the type and quantity of sialic acid in the egg jelly coat of the sea urchin Paracentrotus lividus using capillary LC‐ESI‐MS/MS

B Yeşilyurt, U Şahar, R Deveci - Molecular Reproduction and …, 2015 - Wiley Online Library
Sialic acid is a terminal sugar of carbohydrate chains that participates in numerous
biological events. Recent studies have explored the mechanism of carbohydrate‐mediated …

The enzymology of 2-hydroxyglutarate, 2-hydroxyglutaramate and 2-hydroxysuccinamate and their relationship to oncometabolites

VA Hariharan, TT Denton, S Paraszcszak, K McEvoy… - Biology, 2017 - mdpi.com
Many enzymes make “mistakes”. Consequently, repair enzymes have evolved to correct
these mistakes. For example, lactate dehydrogenase (LDH) and mitochondrial malate …

Mass spectrometric fragmentation analysis of oligosialic and polysialic acids

SP Galuska, H Geyer, C Bleckmann… - Analytical …, 2010 - ACS Publications
Oligosialic and polysialic acids (oligo/polySia) are characterized by high structural diversity,
because of different types of sialic acids and glycosidic linkages. Although several methods …

Glycomic strategy for efficient linkage analysis of di-, oligo-and polysialic acids

SP Galuska, H Geyer, W Mink, P Kaese… - Journal of …, 2012 - Elsevier
Sialic acid polymers of glycoproteins and glycolipids are characterized by a high diversity in
nature and are involved in distinct biological processes depending inter alia on the …

[HTML][HTML] The effect of long-chain bases on polysialic acid-mediated membrane interactions

T Janas, K Nowotarski, T Janas - Biochimica et Biophysica Acta (BBA) …, 2011 - Elsevier
Negatively-charged polysialic acid (polySia) chains are usually membrane-bound and are
often expressed on the surface of neuroinvasive bacterial cells, neural cells, and tumor cells …

Membrane potential-dependent binding of polysialic acid to lipid monolayers and bilayers

K Nowotarski, K Sapoń, M Kowalska… - Cellular and Molecular …, 2013 - degruyter.com
Polysialic acids are linear polysaccharides composed of sialic acid monomers. These
polyanionic chains are usually membrane-bound, and are expressed on the surfaces of …