Introduction: In modern vaccinology and immunotherapy, recombinant proteins more and
more replace whole organisms to induce protective or curative immune responses …

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

Air pollution and climate change are potential drivers for the increasing burden of allergic
diseases. The molecular mechanisms by which air pollutants and climate parameters may …

The development of allergic disease involves the production of IgE antibodies upon allergen
exposure in a process called sensitization. IgE binds to receptors on the surface of mast …

Background The search for intrinsic factors, which account for a protein's capability to act as
an allergen, is ongoing. Fold stability has been identified as a molecular feature that affects …

Background Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has
been identified as the major birch pollen allergen. However, the molecular mechanisms of …

Panallergens comprise various protein families of plant as well as animal origin and are
responsible for wide IgE cross‐reactivity between related and unrelated allergenic sources …

Allergic diseases are considered a major problem for healthcare systems in both developed
and developing countries. House dust mites are well-known triggers of allergic …

Among the vast number of identified protein families, allergens emanate from relatively few
families which translates to only a small fraction of identified protein families. In allergy …

In Brazil and in other tropical areas Zika virus infection was directly associated with clinical
complications as microcephaly in newborn children whose mothers were infected during …