CD123 as a therapeutic target in the treatment of hematological malignancies
U Testa, E Pelosi, G Castelli - Cancers, 2019 - mdpi.com
The interleukin-3 receptor alpha chain (IL-3Rα), more commonly referred to as CD123, is
widely overexpressed in various hematological malignancies, including acute myeloid …
widely overexpressed in various hematological malignancies, including acute myeloid …
Blastic plasmacytoid dendritic cell neoplasm: diagnostic criteria and therapeutical approaches
L Pagano, CG Valentini, S Grammatico… - British journal of …, 2016 - Wiley Online Library
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy
derived from the precursors of plamacytoid dendritic cells, with an aggressive clinical course …
derived from the precursors of plamacytoid dendritic cells, with an aggressive clinical course …
[HTML][HTML] Tagraxofusp in blastic plasmacytoid dendritic-cell neoplasm
N Pemmaraju, AA Lane, KL Sweet… - … England Journal of …, 2019 - Mass Medical Soc
Background Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive
hematologic cancer that is caused by transformed plasmacytoid dendritic cells that …
hematologic cancer that is caused by transformed plasmacytoid dendritic cells that …
Acute myeloid leukemia, version 3.2023, NCCN clinical practice guidelines in oncology
DA Pollyea, JK Altman, R Assi, D Bixby… - Journal of the National …, 2023 - jnccn.org
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized
by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other …
by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other …
Blastic plasmacytoid dendritic cell neoplasm is dependent on BCL2 and sensitive to venetoclax
J Montero, J Stephansky, T Cai, GK Griffin… - Cancer discovery, 2017 - AACR
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive hematologic
malignancy with dismal outcomes for which no standard therapy exists. We found that …
malignancy with dismal outcomes for which no standard therapy exists. We found that …
How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?
F Garnache-Ottou, C Vidal, S Biichlé, F Renosi… - Blood …, 2019 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive leukemia for
which we developed a nationwide network to collect data from new cases diagnosed in …
which we developed a nationwide network to collect data from new cases diagnosed in …
CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies
U Testa, E Pelosi, A Frankel - Biomarker research, 2014 - Springer
Recent studies indicate that abnormalities of the alpha-chain of the interleukin-3 receptor (IL-
3RA or CD123) are frequently observed in some leukemic disorders and may contribute to …
3RA or CD123) are frequently observed in some leukemic disorders and may contribute to …
Blastic plasmacytoid dendritic cell neoplasm: a comprehensive review in pediatrics, adolescents, and young adults (AYA) and an update of novel therapies
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that
can involve the bone marrow, peripheral blood, skin, lymph nodes, and the central nervous …
can involve the bone marrow, peripheral blood, skin, lymph nodes, and the central nervous …
Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients
AE Frankel, JH Woo, C Ahn… - Blood, The Journal …, 2014 - ashpublications.org
This is the first prospective study of treatment of patients with blastic plasmacytoid dendritic
cell neoplasm (BPDCN), an aggressive hematologic malignancy derived from plasmacytoid …
cell neoplasm (BPDCN), an aggressive hematologic malignancy derived from plasmacytoid …
Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of
plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in …
plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in …