[HTML][HTML] Recent preclinical and clinical progress in liposomal doxorubicin

K Aloss, P Hamar - Pharmaceutics, 2023 - mdpi.com
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …

Chitosan-based nanodelivery systems for cancer therapy: Recent advances

A Narmani, SM Jafari - Carbohydrate Polymers, 2021 - Elsevier
Nowadays, cancer is one of the most prominent issues related to human health since it
causes more than one-tenth of death cases throughout the world. On the other hand, routine …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

[HTML][HTML] Targeted protein degradation directly engaging lysosomes or proteasomes

J Kim, I Byun, H Joh, HJ Kim, MJ Lee - Chemical Society Reviews, 2024 - pubs.rsc.org
Targeted protein degradation (TPD) has been established as a viable alternative to
attenuate the function of a specific protein of interest in both biological and clinical contexts …

Glycopolymer-functionalized MOF-808 nanoparticles as a cancer-targeted dual drug delivery system for carboplatin and floxuridine

F Demir Duman, A Monaco, R Foulkes… - ACS Applied Nano …, 2022 - ACS Publications
Codelivery of chemotherapeutics via nanomaterials has attracted much attention over the
last decades due to improved drug delivery to tumor tissues, decreased systemic effects …

Glycopolymers for drug delivery: opportunities and challenges

MH Stenzel - Macromolecules, 2022 - ACS Publications
Glycopolymers are synthetic polymers with pendant sugars, which hold promise for a range
of biomedical applications ranging from tissue engineering to sensing. The known specific …

Mannan-decorated pathogen-like polymeric nanoparticles as nanovaccine carriers for eliciting superior anticancer immunity

Y Xu, S Ma, J Zhao, H Chen, X Si, Z Huang, Z Yu… - Biomaterials, 2022 - Elsevier
Using nanotechnology for cancer vaccine design holds great promise because of the
intrinsic feature of nanoparticles in being captured by antigen-presenting cells (APCs) …

In situ tumor vaccine for lymph nodes delivery and cancer therapy based on small size nanoadjuvant

H Zhang, Y Zhang, H Hu, W Yang, X Xia, L Lei, R Lin… - Small, 2023 - Wiley Online Library
Tumor vaccine is a promising cancer treatment modality, however, the convenient antigens
loading in vivo and efficient delivery of vaccines to lymph nodes (LNs) still remain a …

Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy

J Xu, W Qiu, M Liang, M Ye, J Hu, X Ma, X Shi… - Journal of Controlled …, 2023 - Elsevier
Pyroptosis is a highly inflammatory programmed cell death that activates inflammatory
response, reverses immunosuppression and promotes systemic immune response for solid …

Nanovaccine‐based strategies to overcome challenges in the whole vaccination cascade for tumor immunotherapy

L Qin, H Zhang, Y Zhou, CS Umeshappa, H Gao - Small, 2021 - Wiley Online Library
Nanovaccine‐based immunotherapy (NBI) has received greater attention recently for its
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …