Amphipols for each season
M Zoonens, JL Popot - The Journal of membrane biology, 2014 - Springer
Amphipols (APols) are short amphipathic polymers that can substitute for detergents at the
transmembrane surface of membrane proteins (MPs) and, thereby, keep them soluble in …
transmembrane surface of membrane proteins (MPs) and, thereby, keep them soluble in …
Folding and stabilizing membrane proteins in amphipol A8-35
C Le Bon, A Marconnet, S Masscheleyn, JL Popot… - Methods, 2018 - Elsevier
Membrane proteins (MPs) are important pharmacological targets because of their
involvement in many essential cellular processes whose dysfunction can lead to a large …
involvement in many essential cellular processes whose dysfunction can lead to a large …
Hierarchical molecular dynamics of bovine serum albumin in concentrated aqueous solution below and above thermal denaturation
M Grimaldo, F Roosen-Runge, M Hennig… - Physical Chemistry …, 2015 - pubs.rsc.org
The dynamics of proteins in solution is a complex and hierarchical process, affected by the
aqueous environment as well as temperature. We present a comprehensive study on …
aqueous environment as well as temperature. We present a comprehensive study on …
Membranes do not tell proteins how to fold
JL Popot, DM Engelman - Biochemistry, 2016 - ACS Publications
Which properties of the membrane environment are essential for the folding and
oligomerization of transmembrane proteins? Because the lipids that surround membrane …
oligomerization of transmembrane proteins? Because the lipids that surround membrane …
Folding and stability of integral membrane proteins in amphipols
JH Kleinschmidt, JL Popot - Archives of biochemistry and biophysics, 2014 - Elsevier
Amphipols (APols) are a family of amphipathic polymers designed to keep transmembrane
proteins (TMPs) soluble in aqueous solutions in the absence of detergent. APols have …
proteins (TMPs) soluble in aqueous solutions in the absence of detergent. APols have …
A quasielastic neutron scattering investigation on the molecular self-dynamics of human myelin protein P2
S Laulumaa, MM Koza, T Seydel… - The Journal of …, 2019 - ACS Publications
The human myelin protein P2 is a membrane binding protein believed to maintain correct
lipid composition and organization in peripheral nerve myelin. Its function is related to its …
lipid composition and organization in peripheral nerve myelin. Its function is related to its …
Reconstitution of membrane proteins into platforms suitable for biophysical and structural analyses
PAM Schmidpeter, N Sukomon… - … , purification, and structural …, 2020 - Springer
Integral membrane proteins have historically been challenging targets for biophysical
research due to their low solubility in aqueous solution. Their importance for chemical and …
research due to their low solubility in aqueous solution. Their importance for chemical and …
Formation and Properties of Membrane Protein/Amphipol Complexes
JL Popot, JL Popot - Membrane Proteins in Aqueous Solutions: From …, 2018 - Springer
Complexes between membrane proteins (MPs) and amphipols (APols) can be obtained (i)
by transferring to APols a detergent-solubilized MP,(ii) by directly extracting a membrane …
by transferring to APols a detergent-solubilized MP,(ii) by directly extracting a membrane …
[PDF][PDF] N. et al., Hierarchical molecular dynamics of bovine serum albumin in concentrated aqueous solution below and above thermal denaturation
GMRRF Hennig, MZFZF Jalarvo, F Schreiber - Phys. Chem. Chem. Phys, 1910 - Citeseer
The dynamics of proteins in solution is a complex and hierarchical process, affected by the
aqueous environment as well as temperature. We present a comprehensive study on …
aqueous environment as well as temperature. We present a comprehensive study on …
Global and internal diffusive dynamics of proteins in solution studied by neutron spectroscopy
M Grimaldo - 2016 - tobias-lib.ub.uni-tuebingen.de
Proteins are macromolecules naturally occurring in living cells and organisms, involved in a
great number of processes essential for life, but they can be interesting not only from a …
great number of processes essential for life, but they can be interesting not only from a …