Amphipols (APols) are short amphipathic polymers that can substitute for detergents at the
transmembrane surface of membrane proteins (MPs) and, thereby, keep them soluble in …

Membrane proteins (MPs) are important pharmacological targets because of their
involvement in many essential cellular processes whose dysfunction can lead to a large …

The dynamics of proteins in solution is a complex and hierarchical process, affected by the
aqueous environment as well as temperature. We present a comprehensive study on …

Which properties of the membrane environment are essential for the folding and
oligomerization of transmembrane proteins? Because the lipids that surround membrane …

Amphipols (APols) are a family of amphipathic polymers designed to keep transmembrane
proteins (TMPs) soluble in aqueous solutions in the absence of detergent. APols have …

The human myelin protein P2 is a membrane binding protein believed to maintain correct
lipid composition and organization in peripheral nerve myelin. Its function is related to its …

Integral membrane proteins have historically been challenging targets for biophysical
research due to their low solubility in aqueous solution. Their importance for chemical and …

Complexes between membrane proteins (MPs) and amphipols (APols) can be obtained (i)
by transferring to APols a detergent-solubilized MP,(ii) by directly extracting a membrane …

The dynamics of proteins in solution is a complex and hierarchical process, affected by the
aqueous environment as well as temperature. We present a comprehensive study on …

Proteins are macromolecules naturally occurring in living cells and organisms, involved in a
great number of processes essential for life, but they can be interesting not only from a …