Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers
WM Alenezi, CT Fierheller, N Recio, PN Tonin - Genes, 2020 - mdpi.com
Soon after the discovery of BRCA1 and BRCA2 over 20 years ago, it became apparent that
not all hereditary breast and/or ovarian cancer syndrome families were explained by …
not all hereditary breast and/or ovarian cancer syndrome families were explained by …
The effects of genetic and epigenetic alterations of BARD1 on the development of non-breast and non-gynecological cancers
AK Watters, ES Seltzer, D MacKenzie Jr, M Young… - Genes, 2020 - mdpi.com
Br east Ca ncer 1 (BRCA1) gene is a well-characterized tumor suppressor gene, mutations
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …
Impact of variant reclassification in cancer predisposition genes on clinical care
J Chiang, TH Chia, J Yuen, T Shaw, ST Li… - JCO Precision …, 2021 - ascopubs.org
PURPOSE Genetic testing has clinical utility in the management of patients with hereditary
cancer syndromes. However, the increased likelihood of encountering a variant of uncertain …
cancer syndromes. However, the increased likelihood of encountering a variant of uncertain …
The fellowship of the RING: BRCA1, its partner BARD1 and their liaison in DNA repair and cancer
The breast cancer type 1 susceptibility protein (BRCA1) and its partner–the BRCA1-
associated RING domain protein 1 (BARD1)–are key players in a plethora of fundamental …
associated RING domain protein 1 (BARD1)–are key players in a plethora of fundamental …
Advances in colorectal cancer genomics and transcriptomics drive early detection and prevention
Colorectal carcinoma (CRC) is a high incidence cancer and leading cause of cancer
mortality worldwide. The advances in genomics and transcriptomics in the past decades …
mortality worldwide. The advances in genomics and transcriptomics in the past decades …
Germline heterozygous exons 8–11 pathogenic BARD1 gene deletion reported for the first time in a family with suspicion of a hereditary colorectal cancer syndrome …
S Carrera, AB Rodríguez-Martínez, I Garin… - Hereditary Cancer in …, 2023 - Springer
Background Colorectal cancer (CRC) is a highly prevalent disease in developed countries.
Inherited Mendelian causes account for approximately 5% of CRC cases, with Lynch …
Inherited Mendelian causes account for approximately 5% of CRC cases, with Lynch …
Aktualisierte Kriterien des Deutschen Konsortiums Familiärer Brust-und Eierstockkrebs zur Klassifizierung von Keimbahn-Sequenzvarianten in Risikogenen für …
J Hauke, B Wappenschmidt, U Faust… - Senologie-Zeitschrift …, 2021 - thieme-connect.com
Das Deutsche Konsortium für Familiären Brust-und Eierstockkrebs (GC-HBOC) etablierte
vor über 10 Jahren eine Expertengruppe (VUS Task Force), um die von Einzelzentren des …
vor über 10 Jahren eine Expertengruppe (VUS Task Force), um die von Einzelzentren des …