Modern health care faces several serious challenges, including an ageing population and
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …

Cardiometabolic diseases are a major public-health concern owing to their increasing
prevalence worldwide. These diseases are characterized by a high degree of interindividual …

Genome-wide association studies (GWASs) have provided numerous associations between
human single-nucleotide polymorphisms (SNPs) and health traits. Likewise, metagenome …

The gut is the richest ecosystem of microbes in the human body and has great influence on
our health. Despite many efforts, the set of microbes inhabiting this environment is not fully …

Plasma fasting glucose (FG) levels play a pivotal role in the diagnosis of prediabetes and
diabetes worldwide. Here we investigated FG values using continuous glucose monitoring …

Over the past decade, technological advances have enabled cost-efficient, high-throughput
analysis of different types of omics data in large human cohorts. Here, we explore insights …

Objective To explore the interplay between dietary modifications, microbiome composition
and host metabolic responses in a dietary intervention setting of a personalised postprandial …

Despite its rising prevalence, diabetes diagnosis still relies on measures from blood tests.
Technological advances in continuous glucose monitoring (CGM) devices introduce a …

Background Genome-wide association studies (GWASs) associate phenotypes and genetic
variants across a study cohort. GWASs require large-scale cohorts with both phenotype and …

Recent advances in self-supervised learning enabled novel medical AI models, known as
foundation models (FMs) that offer great potential for characterizing health from diverse …