Beyond E-cadherin: roles of other cadherin superfamily members in cancer
F Van Roy - Nature Reviews Cancer, 2014 - nature.com
Abstract Loss of cadherin 1 (CDH1; also known as epithelial cadherin (E-cadherin)) is used
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …
DNA hypomethylation in cancer cells
M Ehrlich - Epigenomics, 2009 - Taylor & Francis
DNA hypomethylation was the initial epigenetic abnormality recognized in human tumors.
However, for several decades after its independent discovery by two laboratories in 1983, it …
However, for several decades after its independent discovery by two laboratories in 1983, it …
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
RA Gupta, N Shah, KC Wang, J Kim, HM Horlings… - nature, 2010 - nature.com
Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome,,
yet their potential involvement in human disease is not well understood,. Recent studies of …
yet their potential involvement in human disease is not well understood,. Recent studies of …
Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations
A three-dimensional chromatin state underpins the structural and functional basis of the
genome by bringing regulatory elements and genes into close spatial proximity to ensure …
genome by bringing regulatory elements and genes into close spatial proximity to ensure …
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
GC Hon, RD Hawkins, OL Caballero, C Lo… - Genome …, 2012 - genome.cshlp.org
While genetic mutation is a hallmark of cancer, many cancers also acquire epigenetic
alterations during tumorigenesis including aberrant DNA hypermethylation of tumor …
alterations during tumorigenesis including aberrant DNA hypermethylation of tumor …
Associations with early-life socio-economic position in adult DNA methylation
N Borghol, M Suderman, W McArdle… - International journal …, 2012 - academic.oup.com
Background Disadvantaged socio-economic position (SEP) in childhood is associated with
increased adult mortality and morbidity. We aimed to establish whether childhood SEP was …
increased adult mortality and morbidity. We aimed to establish whether childhood SEP was …
Protocadherins at the crossroad of signaling pathways
A Pancho, T Aerts, MD Mitsogiannis… - Frontiers in Molecular …, 2020 - frontiersin.org
Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …
Broad epigenetic signature of maternal care in the brain of adult rats
Background Maternal care is associated with long-term effects on behavior and epigenetic
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …
Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine
B Pasculli, R Barbano, P Parrella - Seminars in cancer biology, 2018 - Elsevier
In the last years, mortality from breast cancer has declined in western countries as a
consequence of a more widespread screening resulting in earlier detection, as well as an …
consequence of a more widespread screening resulting in earlier detection, as well as an …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …