Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate
species and provides maximum durability that allows teeth to function as weapons and/or …

Growth in production of manufactured goods and the use of nanomaterials in consumer
products has mounted in the past few decades. Nanotoxicology or toxicity assessment of …

The ligand-stimulated epidermal growth factor receptor (EGFR) has been extensively
studied in the analysis of molecular mechanisms regulating endocytic traffic and the role of …

Endocytosis is required for internalization of micronutrients and turnover of membrane
components. Endophilin has been assigned as a component of clathrin-mediated …

Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …

Highlights•Transcytosis is actively suppressed in CNS endothelial cells for barrier
integrity.•Transcytosis is dynamically regulated during development and …

Parkinson's disease (PD) is characterized pathologically by intraneuronal inclusions called
Lewy bodies, largely comprised of α-synuclein. Multiplication of the α-synuclein gene locus …

We discuss here the variety of approaches that have been taken to inhibit different forms of
endocytosis. Typically, both non-specific and specific chemical inhibitors of endocytosis are …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …