The LOD paradox: when lower isn't always better in biosensor research and development

H Moulahoum, F Ghorbanizamani - Biosensors and Bioelectronics, 2024 - Elsevier
Biosensor research has long focused on achieving the lowest possible Limits of Detection
(LOD), driving significant advances in sensitivity and opening up new possibilities in …

The challenges of developing biosensors for clinical assessment: A review

BA Prabowo, PD Cabral, P Freitas, E Fernandes - Chemosensors, 2021 - mdpi.com
Emerging research in biosensors has attracted much attention worldwide, particularly in
response to the recent pandemic outbreak of coronavirus disease 2019 (COVID-19) …

Rapid and multiplex detection of nosocomial pathogens on a phage‐based magnetoresistive lab‐on‐chip platform

AP Cunha, R Henriques, S Cardoso… - Biotechnology and …, 2021 - Wiley Online Library
Nosocomial or hospital‐acquired infections (HAIs) have a major impact on mortality
worldwide. Enterococcus and Staphylococcus are among the leading causes of HAIs and …

Fibronectin containing alternatively spliced extra domain A interacts at the central and c-terminal domain of Toll-like receptor-4

S Gupta, A Ali, S Pandey, IA Khan, P Prakash - Scientific Reports, 2022 - nature.com
Extra domain A of cellular fibronectin (FN-EDA) is known to cause insulin resistance,
atherosclerosis, tissue fibrosis, ischemic stroke and exaggerated myocardial reperfusion …

A pump-free microfluidic device for fast magnetic labeling of ischemic stroke biomarkers

BA Prabowo, E Fernandes, P Freitas - Analytical and bioanalytical …, 2022 - Springer
This research proposes a low-cost and simple operation microfluidic chip to enhance the
magnetic labeling efficiency of two ischemic stroke biomarkers: cellular fibronectin (c-Fn) …

Association of matrix metalloproteinase 9 and cellular fibronectin and outcome in acute ischemic stroke: a systematic review and meta-analysis

L Wang, L Deng, R Yuan, J Liu, Y Li, M Liu - Frontiers in Neurology, 2020 - frontiersin.org
Introduction: The role of matrix metalloproteinase 9 (MMP-9) and cellular fibronectin (c-Fn) in
acute ischemic stroke is controversial. We systematically reviewed the literature to …

[HTML][HTML] Loganin attenuates the inflammation, oxidative stress, and apoptosis through the JAK2/STAT3 pathway in cerebral ischemia-reperfusion injury

Y Xi, X Hou, Y Huang, Y Zhou, Y Chen, Y Wang… - Journal of Stroke and …, 2025 - Elsevier
Background Loganin, a monoterpene iridoid glycoside derived from Cornus officinalis Sieb.
Et Zucc, has been reported to have anti-inflammatory and antioxidant activity. Nevertheless …

FTA-LAMP based biosensor for a rapid in-field detection of Globodera pallida—the pale potato cyst nematode

MJ Camacho, DC Albuquerque, ML Inácio… - … in Bioengineering and …, 2024 - frontiersin.org
The combination of a sensitive and specific magnetoresistive sensing device with an easy
DNA extraction method and a rapid isothermal amplification is presented here targeting the …

Combined detection of molecular and serological signatures of viral infections: The dual assay concept

DC Albuquerque, VC Martins, E Fernandes… - Biosensors and …, 2022 - Elsevier
The recent worldwide spread of viral infections has highlighted the need for accurate, fast,
and inexpensive disease diagnosis and monitorization methods. Current diagnostics tend to …

Timely and blood-based multiplex molecular profiling of acute stroke

A Dias, I Silva, IM Pinto, LF Maia - Life, 2021 - mdpi.com
Stroke is a leading cause of death and disability in the world. To address such a problem,
early diagnosis and tailored acute treatment represent one of the major priorities in acute …