Recent advances in aptamer discovery and applications

Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

Programmable and multifunctional DNA‐based materials for biomedical applications

Y Zhang, J Tu, D Wang, H Zhu, SK Maity… - Advanced …, 2018 - Wiley Online Library
DNA encodes the genetic information; recently, it has also become a key player in material
science. Given the specific Watson–Crick base‐pairing interactions between only four types …

Chemical modification of aptamers for increased binding affinity in diagnostic applications: Current status and future prospects

JP Elskens, JM Elskens, A Madder - International journal of molecular …, 2020 - mdpi.com
Aptamers are short single stranded DNA or RNA oligonucleotides that can recognize
analytes with extraordinary target selectivity and affinity. Despite their promising properties …

Biosensors: Classifications, medical applications, and future prospective

HA Alhadrami - Biotechnology and applied biochemistry, 2018 - Wiley Online Library
Biosensors are devices that combine a biological material with a suitable platform for
detection of pathogenic organisms, carcinogenic, mutagenic, and/or toxic chemicals or for …

Colorimetric aptasensor for on-site detection of oxytetracycline antibiotic in milk

K Birader, P Kumar, Y Tammineni, JA Barla, S Reddy… - Food chemistry, 2021 - Elsevier
Oxytetracycline (OTC), one of the largely used antibiotic in veterinary practice has been
banned due to its potential side effects. Development of a field applicable and affordable kit …

Aptamer-based biosensors for detection of lead (ii) ion: a review

D Yang, X Liu, Y Zhou, L Luo, J Zhang, A Huang… - Analytical …, 2017 - pubs.rsc.org
Lead (II) ion (Pb2+) contamination can be accumulated along the food chain and cause a
serious threat to public health. Plenty of research effort has thus been devoted to the …

Aptamer based tools for environmental and therapeutic monitoring: A review of developments, applications, future perspectives

B Kudłak, M Wieczerzak - Critical Reviews in Environmental …, 2020 - Taylor & Francis
Nucleic acids in the form of aptamers play a growing and significant role in the targeted and
rapid analysis of environmental sample composition and medical analyses. In this paper, the …

Aptameric biosensor for the sensitive detection of major shrimp allergen, tropomyosin

R Chinnappan, AA Rahamn, R AlZabn, S Kamath… - Food Chemistry, 2020 - Elsevier
The development of a sensitive and rapid detection approach for allergens in various food
matrices is essential to assist patients in managing their allergies. The most common …

Nanomaterial-based fluorescent biosensor for food safety analysis

J Zhou, Y Gui, X Lv, J He, F Xie, J Li, J Cai - Biosensors, 2022 - mdpi.com
Food safety issues have become a major threat to public health and have garnered
considerable attention. Rapid and effective detection methods are crucial for ensuring food …

Advances of aptamer-based small-molecules sensors in body fluids detection

L Chen, G Yang, F Qu - Talanta, 2024 - Elsevier
The field of aptamer-based sensing has evolved considerably over the past three decades.
The aptamer sensor-based detection of small-molecule targets in body fluids is designed for …