Abdominal obesity, adipokines and non-communicable diseases

D Dhawan, S Sharma - The Journal of steroid biochemistry and molecular …, 2020 - Elsevier
Abdominal obesity may be defined as excess deposits of fat in the abdominal region. It is a
common health condition seen in South Asians and is positively related to non …

Endothelial permeability, LDL deposition, and cardiovascular risk factors—A review

S Mundi, M Massaro, E Scoditti… - Cardiovascular …, 2018 - academic.oup.com
Early atherosclerosis features functional and structural changes in the endothelial barrier
function that affect the traffic of molecules and solutes between the vessel lumen and the …

Neutrophils actively contribute to obesity-associated inflammation and pathological complications

E Uribe-Querol, C Rosales - Cells, 2022 - mdpi.com
Obesity is characterized by an increase in body weight associated with an exaggerated
enlargement of the adipose tissue. Obesity has serious negative effects because it is …

New insights into the role of adipose tissue in thrombosis

G Vilahur, S Ben-Aicha, L Badimon - Cardiovascular research, 2017 - academic.oup.com
Central obesity is independently associated with an elevated risk of cardiovascular disease,
particularly thrombotic complications. Increasing data supports a link between excess body …

[HTML][HTML] Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target

MJ Hughes, HM McGettrick… - European Respiratory …, 2020 - Eur Respiratory Soc
Multimorbidity is increasingly common and current healthcare strategies are not always
aligned to treat this complex burden of disease. COPD, type-2 diabetes mellitus (T2D) and …

Gut microbiome, inflammation, and cerebrovascular function: link between obesity and cognition

L Olsthoorn, D Vreeken, AJ Kiliaan - Frontiers in Neuroscience, 2021 - frontiersin.org
Obesity affects 13% of the adult population worldwide and this number is only expected to
increase. Obesity is known to have a negative impact on cardiovascular and metabolic …

The role of secretory activity molecules of visceral adipocytes in abdominal obesity in the development of cardiovascular disease: a review

YI Ragino, EM Stakhneva, YV Polonskaya… - Biomolecules, 2020 - mdpi.com
Adipose tissue is considered one of the endocrine organs in the body because of its ability
to synthesize and release a large number of hormones, cytokines, and growth and …

Effectiveness of magnolol, a lignan from Magnolia bark, in diabetes, its complications and comorbidities—a review

K Szałabska-Rąpała, W Borymska… - International Journal of …, 2021 - mdpi.com
Diabetes mellitus is a chronic metabolic disease characterized by disturbances in
carbohydrate, protein, and lipid metabolism, often accompanied by oxidative stress …

The influence of antioxidants on oxidative stress-induced vascular aging in obesity

H Sharebiani, S Keramat, A Chavoshan, B Fazeli… - Antioxidants, 2023 - mdpi.com
Obesity is a worldwide trend that is growing in incidence very fast. Adipose tissue
dysfunction caused by obesity is associated with the generation of oxidative stress. Obesity …

Plasminogen Activator Inhibitor-1 in poorly controlled vs well controlled Type-2 Diabetes Mellitus patients: A case-control study in a district hospital in Ghana

C Nkansah, O Addai-Mensah, K Mensah, M Owusu… - PLoS …, 2021 - journals.plos.org
Background Hypofibrinolysis resulting from the up-regulation of plasminogen activator
inhibitor-1 (PAI-1) usually occurs in patients with type 2 diabetes mellitus (T2DM), rendering …