Gene body methylation (gbM) is an epigenetic mark where gene exons are methylated in
the CG context only, as opposed to CHG and CHH contexts (where H stands for A, C, or T) …

Rapid development of high-throughput single-cell RNA sequencing (scRNA-seq)
technologies offers exciting opportunities to reveal new and rare cell types, previously …

Mistakes in the maintenance of CG methylation are a source of heritable epimutations in
plants. Multigenerational surveys indicate that the rate of these stochastic events varies …

Gene body methylation (gbM) is a widely conserved epigenetic feature of plant genomes.
Efforts to delineate the mechanisms by which gbM contributes to transcriptional regulation …

The ability to target epigenetic marks like DNA methylation to specific loci is important in
both basic research and in crop plant engineering. However, heritability of targeted DNA …

In plants, epigenetic regulation is critical for silencing transposons and maintaining proper
gene expression. However, its impact on the genome-wide transcription initiation landscape …

For survival in the natural environment, plants have evolved a 'bet-hedging'strategy where
individual variation is high and a range of phenotypes is produced. When faced with …

A subset of genes in plant genomes are labeled with DNA methylation specifically at CG
residues. These genes, known as gene-body methylated (gbM), have a number of …

Stochastic changes in DNA methylation (ie, spontaneous epimutations) contribute to
methylome diversity in plants. Here, we describe AlphaBeta, a computational method for …

Catharanthus roseus produces a wide spectrum of monoterpene indole alkaloids (MIAs).
MIA biosynthesis requires a tightly coordinated pathway involving more than 30 enzymatic …