Methods and compositions for inhibition of angiogenesis

R D'amato - US Patent 5,712,291, 1998 - Google Patents
The present invention comprises a group of compounds that effectively inhibit angiogenesis.
More speci? cally, thalido mide and various related compounds such as thalidomide …

Substituted phenethylsulfones and method of reducing TNFα levels

GW Muller, HW Man - US Patent 6,020,358, 2000 - Google Patents
Phenethylsulfones substituted in the position α to the phenyl group with a 1-oxoisoindoline
or 1, 3-dioxoisoindoline group reduce the levels of TNFα in a mammal. Typical embodiments …

Methods and compositions for inhibition of angiogenesis with EM-138

SJ Green, GM Swartz Jr, JH Shah, J Madsen… - US Patent …, 2003 - Google Patents
The present invention comprises a group of compounds that effectively inhibit angiogenesis.
More specifically, the invention comprises the compound EM-138 and its use in the …

Methods and compositions for inhibition of angiogenesis

R D'amato - US Patent 6,114,355, 2000 - Google Patents
The present invention comprises a group of compounds that effectively inhibit angiogenesis.
More specifically, thalidomide and various related compounds such as thalidomide …

Methods and compositions for inhibition of angiogenesis with EM-138

R D'amato - US Patent 6,469,045, 2002 - Google Patents
The present invention comprises a group of compounds that effectively inhibit angiogenesis.
More specifically, thalidomide and various related compounds such as thalidomide …

Amino derivatives of EM-138 and methods of treating angiogenesis with same

R D'amato - US Patent 6,420,414, 2002 - Google Patents
The present invention comprises a group of compounds that effectively inhibit angiogenesis.
More specifically, thalidomide and various related compounds such as thalidomide …

Methods and compositions for inhibition of angiogenesis with EM-138

R D'amato - US Patent 6,977,268, 2005 - Google Patents
The present invention comprises a group of compounds that effectively inhibit angiogenesis.
More Specifically, thalido mide and various related compounds Such as thalidomide …

Substituted 1, 3, 4-oxadiazoles and a method of reducing TNF-alpha level

HW Man, GW Muller - US Patent 6,326,388, 2001 - Google Patents
Substituted 1, 3, 4-oxadiazole compounds reduce the levels of TNFC. in a mammal. Typical
embodiments are 2-1-(3-cyclopentyloxy-4-methoxyphenyl)-2-(1, 3, 4-oxadiazol-2-yl) ethyl-5 …

Analogs of 2-Phthalimidinoglutaric acid

SJ Green, GM Swartz Jr, JH Shah, J Madsen… - US Patent …, 2004 - Google Patents
The invention provides new and useful analogs of 2-phthalimidinoglutaric acid. These
analogs include DL-2-methyl-2-phthalimidinoglutaric acid and hydroxylated analogs of 2 …

Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures

JR Gorman - US Patent App. 12/307,902, 2010 - Google Patents
Methods for identifying subjects who could benefit therapeu tically from administration of a
high specificity cytokine inhibitor are provided. Subjects that are identified include those that …