Environmental pollutants induce NLRP3 inflammasome activation and pyroptosis: roles and mechanisms in various diseases

Y Mou, W Liao, Y Liang, Y Li, M Zhao, Y Guo… - Science of The Total …, 2023 - Elsevier
Environmental pollution is changing with economic development. Most environmental
pollutants are characterized by stable chemical properties, strong migration, potential …

Intestinal homeostasis in the gut-lung-kidney axis: a prospective therapeutic target in immune-related chronic kidney diseases

X Liu, X Wang, P Zhang, Y Fang, Y Liu, Y Ding… - Frontiers in …, 2023 - frontiersin.org
In recent years, the role of intestinal homeostasis in health has received increasing interest,
significantly improving our understanding of the complex pathophysiological interactions of …

[HTML][HTML] Disease types and pathogenic mechanisms induced by PM2. 5 in five human systems: An analysis using omics and human disease databases

S Zhang, X Li, L Zhang, Z Zhang, X Li, Y Xing… - Environment …, 2024 - Elsevier
Atmospheric fine particulate matter (PM 2.5) can harm various systems in the human body.
Due to limitations in the current understanding of epidemiology and toxicology, the disease …

[HTML][HTML] PM2. 5 induces renal tubular injury by activating NLRP3-mediated pyroptosis

W Chen, Y Luo, J Quan, J Zhou, B Yi… - … and Environmental Safety, 2023 - Elsevier
Abstract Fine particulate matter (PM 2.5)-related health issues have received increasing
attention as a worldwide public health problem, and PM 2.5-related chronic kidney disease …

Effects of solvent extracted organic matter from outdoor air pollution on human type II pneumocytes: Molecular and proteomic analysis

A Déciga-Alcaraz, CTG de León, JM Montor… - Environmental …, 2023 - Elsevier
Outdoor air pollution is responsible for the exacerbation of respiratory diseases in humans.
Particulate matter with an aerodynamic diameter≤ 2.5 μm (PM 2.5) is one of the main …

Associations between short-term exposure to PM2. 5, NO2 and O3 pollution and kidney-related conditions and the role of temperature-adjustment specification: A …

L Chu, K Chen, Q Di, S Crowley, R Dubrow - Environmental Pollution, 2023 - Elsevier
Epidemiologic evidence on the relationship between air pollution and kidney disease
remains inconclusive. We evaluated associations between short-term exposure to PM 2.5 …

[HTML][HTML] Air quality and kidney health: Assessing the effects of PM10, PM2. 5, CO, and NO2 on renal function in primary glomerulonephritis

J Yi, SH Kim, H Lee, HJ Chin, JY Park, J Jung… - Ecotoxicology and …, 2024 - Elsevier
Background While extensive studies have elucidated the relationships between exposure to
air pollution and chronic diseases, such as cardiovascular disorders and diabetes, the …

[HTML][HTML] Environmental change, changing biodiversity and infections–lessons for kidney health community

P Meena, V Jha - Kidney International Reports, 2023 - Elsevier
There is a direct and accelerating connection between ongoing environmental change, the
unprecedented decline in biodiversity, and the increase in infectious disease epidemiology …

Environmental pollution to kidney disease: an updated review of current knowledge and future directions

XQ Lao, Y Bo, D Chen, K Zhang, CC Szeto - Kidney International, 2024 - Elsevier
Environmental pollution significantly impacts global disease burden. However, the
contribution of environmental pollution to kidney disease is often overlooked in nephrology …

Role of AhR-Hsp90-MDM2-mediated VDR ubiquitination in PM2. 5-induced renal toxicity

P Zhang, L Wang, J Zhang, Q An, Y Wang, N Hu… - Environmental …, 2024 - Elsevier
Background and objectives The kidney is a primary target for the accumulation of particulate
matter (PM2. 5). This study aimed to investigate PM2. 5-induced renal toxicity mechanisms …