Triply periodic minimal surface structures and related geometries are widely identified in
many natural systems, such as biological membranes and biophotonic structures in butterfly …

Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …

RNA therapeutics have the potential to resolve a myriad of genetic diseases. Lipid
nanoparticles (LNPs) are among the most successful RNA delivery systems. Expanding their …

The phase behavior and physical properties of lipids in biological membranes are
exquisitely sensitive to changes in temperature (50). Because membranes (a) act as …

Mammalian cell membranes are composed of a complex array of glycerophospholipids and
sphingolipids that vary in head-group and acyl-chain composition. In a given cell type …

Docosahexaenoic acid (DHA) with 22-carbons and 6 double bonds is the extreme example
of an ω-3 polyunsaturated fatty acid (PUFA). DHA has strong medical implications since its …

LIPID TRANSMEMBRANE DISTRIBUTION Methods used to determine lipid asymmetry
None of the methods utilized is' perfect'. Each one has its own drawbacks and advantages …

IV Thermodynarmcs of non-lamellar phase transitions A Lipid self-assembly and the
hydrophoblc effect B Intermolecular Interactions C Interfaclal curvature D Lateral expansion …

The mechanism whereby cationic lipids destabilize cell membranes to facilitate the
intracellular delivery of macromolecules such as plasmid DNA or antisense oligonucleotides …

This chapter will describe the types of liquid-crystalline phases adopted by lipids in water,
and the factors which control phase stability. Even single lipid systems can display a quite …