The double-stranded RNA-dependent protein kinase PKR plays multiple roles in cells, in
response to different stress situations. As a member of the interferon (IFN)‑Stimulated …

Viruses are small obligatory parasites and as a consequence, they have developed
sophisticated strategies to exploit the host cell's functions to create an environment that …

Most viruses with non-segmented single stranded RNA genomes complete their life cycle in
the cytoplasm of infected cells. However, despite undergoing replication in the cytoplasm …

Hepatitis C virus (HCV) infection is accompanied by the induction of oxidative stress,
mediated by several virus proteins, the most prominent being the nucleocapsid protein (HCV …

Hepatitis C virus (HCV) infection induces formation of a membranous web structure in the
host cell cytoplasm where the viral genome replicates and virions assemble. The …

The hepatitis C virus (HCV) is a positive strand RNA virus of the Flavivirus family that
replicates in the cytoplasm of infected hepatocytes. Previously, several nuclear localization …

Background Chikungunya virus (CHIKV) is an alphavirus of the Togaviridae family. After
autoproteolytic cleavage, the CHIKV capsid protein (CP) is involved in RNA binding and …

Hepatitis C virus (HCV), which is a major causative agent of blood-borne hepatitis, has
chronically infected about 170 million individuals worldwide and leads to chronic infection …

Hepatitis C virus (HCV) core protein is essential for virus assembly. HCV core protein was
expressed and purified. Aptamers against core protein were raised through the selective …

In this study, newly identified host interactors of hepatitis C virus (HCV) proteins were
assessed for a role in modulating the innate immune response. The analysis revealed …