The prevalence of neurodegenerative disease (ND) is increasing, partly owing to extensions
in lifespan, with a larger percentage of members living to an older age, but the ND aetiology …

In a literature survey, Chernoff et al.(2017) dismissed the hypothesis that chronic exposure
to β-N-methylamino-L-alanine (BMAA) may be a risk factor for progressive …

Amino acids are present in a variety of matrices from biological fluids to plant and animal
tissues. We discuss options for amino acid extraction, sample clean-up and protein …

The neurotoxin β-N-methylamino-L-alanine (BMAA) is a natural non-proteinogenic diamino
acid produced by several species of both prokaryotic (cyanobacteria) and eukaryotic …

Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive
cyanopeptides in freshwater, marine, and terrestrial ecosystems. The health significance of …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease affecting
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …

The compound BMAA (β-N-methylamino-L-alanine) has been postulated to play a
significant role in four serious neurological human diseases: Amyotrophic Lateral Sclerosis …

Background After decades of research recognizing it as a complex multifactorial disorder,
sporadic Alzheimer's disease (sAD) still has no known etiology. Adding to the myriad of …

The blood‐brain barrier (BBB) and the blood‐spinal cord barrier (BSCB) are responsible for
controlling the microenvironment within neural tissues in humans. These barriers are …

Research interest in a non-protein amino acid β-N-methylamino-L-alanine (BMAA) arose
due to the discovery of a connection between exposure to BMAA and the occurrence of …