Objective To update and expand upon prior Osteoarthritis Research Society International
(OARSI) guidelines by developing patient-focused treatment recommendations for …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective, widely used analgesics. For
the past 2 decades, considerable attention has been focused on their cardiovascular safety …

Inflammatory cytokines are commonly elevated in acute depression and are associated with
resistance to monoaminergic treatment. To examine the potential role of cytokines in the …

Although turmeric and its curcumin-enriched extracts have been used for treating arthritis, no
systematic review and meta-analysis of randomized clinical trials (RCTs) have been …

Surveys and registries are needed to verify that real-life daily practice is in keeping with what
is recommended in the guidelines, thus completing the loop between clinical research …

Well-heeled American corporations have long had a financial stake in undermining scientific
consensus and manufacturing uncertainty. In The Triumph of Doubt, former Obama and …

Complex interactions between the immune system and the brain might have important
aetiological and therapeutic implications for neuropsychiatric brain disorders. A possible …

Importance Longitudinal studies have linked the systemic inflammatory markers interleukin 6
(IL-6) and C-reactive protein (CRP) with the risk of developing heart disease and diabetes …

Pain which persists after healing is expected to have taken place, or which exists in the
absence of tissue damage, is termed chronic pain. By definition chronic pain cannot be …

PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART
DISEASE AND CANCER. In his latest ground-breaking book, Peter C Gotzsche exposes the …