[HTML][HTML] Diabetes as a risk factor for Alzheimer's disease in the Middle East and its shared pathological mediators

RL Jayaraj, S Azimullah, R Beiram - Saudi Journal of Biological Sciences, 2020 - Elsevier
The incidence of Alzheimer's disease (AD) has risen exponentially worldwide over the past
decade. A growing body of research indicates that AD is linked to diabetes mellitus (DM) …

Pathophysiological mechanisms linking type 2 diabetes and dementia: review of evidence from clinical, translational and epidemiological research

OY Bello-Chavolla, NE Antonio-Villa… - Current diabetes …, 2019 - ingentaconnect.com
Background: Type 2 diabetes represents an increasing health burden world-wide and its
prevalence in particularly higher in elderly population. Consistent epidemiological evidence …

Diabetes duration and the risk of dementia: a cohort study based on German health claims data

C Reinke, N Buchmann, A Fink, C Tegeler… - Age and …, 2022 - academic.oup.com
Objective Diabetes is a risk factor for dementia but little is known about the impact of
diabetes duration on the risk of dementia. We investigated the effect of type 2 diabetes …

[HTML][HTML] Risk of dementia in patients hospitalised with type 1 and type 2 diabetes in England, 1998–2011: a retrospective national record linkage cohort study

K Smolina, CJ Wotton, MJ Goldacre - Diabetologia, 2015 - Springer
Aims/hypothesis Type 2 diabetes increases the risk of subsequent dementia. Our objective
was to determine whether a similar risk of subsequent dementia is associated with type 1 …

[HTML][HTML] HMGB1 signaling pathway in diabetes-related dementia: Blood-brain barrier breakdown, brain insulin resistance, and Aβ accumulation

J Jeong, DH Lee, J Song - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Diabetes contributes to the onset of various diseases, including cancer and cardiovascular
and neurodegenerative diseases. Recent studies have highlighted the similarities and …

Long-term glycemic control and dementia risk in type 1 diabetes

ME Lacy, P Gilsanz, AJ Karter, CP Quesenberry… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Individuals with type 1 diabetes have experienced an increase in life
expectancy, yet it is unknown what level of glycemic control is ideal for maintaining late-life …

Causes of death according to death certificates in individuals with dementia: a cohort from the Swedish dementia registry

S Garcia‐Ptacek, I Kåreholt… - Journal of the …, 2016 - Wiley Online Library
Objectives The causes of death in dementia are not established, particularly in rarer
dementias. The aim of this study is to calculate risk of death from specific causes for a …

[HTML][HTML] A cross-sectional study of Alzheimer-related proteins in women with polycystic ovary syndrome

AE Butler, ASM Moin, T Sathyapalan… - International Journal of …, 2024 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in women of
reproductive age, and several risk factors found in PCOS are associated with an increased …

Severe hypoglycemia increases dementia risk and related mortality: a nationwide, population-based cohort study

E Han, K Han, BW Lee, ES Kang… - The Journal of …, 2022 - academic.oup.com
Context There are few studies focused on the relationship between hypoglycemia and new-
onset dementia in patients with type 2 diabetes and no study regarding mortality of dementia …

[HTML][HTML] The effect of comorbidities on survival in persons with Alzheimer's disease: a matched cohort study

B Rajamaki, S Hartikainen, AM Tolppanen - BMC geriatrics, 2021 - Springer
Background Alzheimer's disease (AD) is one of the leading causes of death world-wide, but
little is known on the role of comorbidities on mortality among people with AD. We studied …