Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

Background Engineered nanomaterials (ENM) are used extensively in food products to fulfill
a number of roles, including enhancement of color and texture, for nutritional fortification …

Over the last decades, the growing understanding on DNA damage response (DDR)
pathways has broadened the therapeutic landscape in oncology. It is becoming increasingly …

Ribonucleic acid (RNA) therapeutics are being actively researched as a therapeutic
modality in preclinical and clinical studies. They have become one of the most ubiquitously …

The US National Nanotechnology Initiative (NNI) defines nanotechnology as “the
understanding and control of matter at dimensions between approximately 1 and 100 nm …

Ataxia telangiectasia mutated and RAD3 related (ATR) protein kinase plays critical roles in
ensuring DNA replication, DNA repair, and cell cycle control in response to replication …

Background: Microplastics (MPs) are a new global environmental threat. Previously, we
showed the biodistribution of MPs using [64 Cu] polystyrene (PS) and PET in mice. Here, we …

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancers, and overall
survival rates have barely improved over the past five decades. The antimetabolite …

The physico-chemical properties of nanoparticle (NP), such as particle size, surface defects,
crystallinity and accessible surface, affect NP photocatalytic activity that in turn defines the …

Inhibition of ribonucleotide reductase (RNR), the rate-limiting enzyme in the synthesis of
deoxyribonucleotides, causes DNA replication stress and activates the ataxia telangiectasia …