Pathologic Mechanisms Underlying the Clinical Findings in Canine Leishmaniosis due to Leishmaniainfantum/chagasi

AF Koutinas, CK Koutinas - Veterinary Pathology, 2014 - journals.sagepub.com
In dogs with symptomatic or asymptomatic leishmaniosis, Leishmania infantum appears to
induce a mixed Th1/Th2 immune response that in the sick dog may eventually result in …

Biomarkers Associated With Leishmania infantum Exposure, Infection, and Disease in Dogs

C Maia, L Campino - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Canine leishmaniosis (CanL) is a vector-borne disease caused by the protozoan
Leishmania (Leishmania) infantum species [syn. L.(L.) infantum chagasi species in the …

Insights on adaptive and innate immunity in canine leishmaniosis

S Hosein, DP Blake, L Solano-Gallego - Parasitology, 2017 - cambridge.org
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a
systemic disease, which can present with variable clinical signs, and clinicopathological …

Deception and Manipulation: The Arms of Leishmania, a Successful Parasite

P Cecílio, B Pérez-Cabezas, N Santarém… - Frontiers in …, 2014 - frontiersin.org
Leishmania spp. are intracellular parasitic protozoa responsible for a group of neglected
tropical diseases, endemic in 98 countries around the world, called leishmaniasis. These …

Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease

BM Roatt, RDO Aguiar-Soares, W Coura-Vital… - Frontiers in …, 2014 - frontiersin.org
Leishmaniasis has several clinical forms: self-healing or chronic cutaneous leishmaniasis or
post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; visceral leishmaniasis (VL) …

An overview of immunotherapeutic approaches against canine visceral leishmaniasis: what has been tested on dogs and a new perspective on improving treatment …

AAM Gonçalves, JC Leite, LA Resende… - Frontiers in Cellular …, 2019 - frontiersin.org
Visceral leishmaniasis (VL), caused by digenetic protozoa of the genus Leishmania, is the
most severe form of leishmaniasis. Leishmania infantum is one of the species responsible …

The roles of mast cells in parasitic protozoan infections

F Lu, S Huang - Frontiers in Immunology, 2017 - frontiersin.org
Protozoan parasites such as Plasmodium spp., Leishmania spp., Trypanosoma spp., and
Toxoplasma gondii are major causes of parasitic diseases in both humans and animals. The …

Cutaneous involvement in canine leishmaniosis due to Leishmania infantum (syn. L. chagasi)

MN Saridomichelakis, AF Koutinas - Veterinary Dermatology, 2014 - Wiley Online Library
Background Canine leishmaniosis, a zoonotic infectious disease caused by Leishmania
infantum (syn. L. chagasi), is fairly common in endemic areas, and skin lesions are the most …

Neutrophils and Visceral Leishmaniasis: Impact on innate immune response and cross‐talks with macrophages and dendritic cells

M Kupani, RK Pandey… - Journal of Cellular …, 2021 - Wiley Online Library
Neutrophils with their array of microbicidal activities are the first innate immune cells to
guard against infection. They are also most crucial for the host's initial defense against …

Eosinophils and mast cells in leishmaniasis

NE Rodríguez, ME Wilson - Immunologic research, 2014 - Springer
Leishmania spp. are parasitic protozoa endemic in tropical and subtropical regions and the
causative agent of leishmaniasis, a collection of syndromes whose clinical manifestations …