Chloride transport across cell membranes is broadly involved in epithelial fluid transport, cell
volume and pH regulation, muscle contraction, membrane excitability, and organellar …

Abstract Purpose of Review To review the role of ocular surface epithelial (corneal and
conjunctival) ion transporters in the pathogenesis and treatment of dry eye disease (DED) …

Dry eye disease is one of the most common diseases, with increasing prevalence in many
countries, but treatment options are limited. Cystic fibrosis transmembrane conductance …

Cystic fibrosis transmembrane conductance regulator (CFTR) is highly expressed on the
ocular epithelium and plays a pivotal role in the fluid secretion driven by chloride transport …

Dry eye disease (DED) is one of the most prevalent ocular diseases but has limited
treatment options. Cystic fibrosis transmembrane conductance regulator (CFTR), a major …

Purpose Ocular surface hydration is critical for eye health and its impairment can lead to dry
eye disease. Extracellular calcium-sensing receptor (CaSR) is regulator of ion transport in …

We evaluate the difference in vulnerability to desiccating stress (DS) between the corneal
and conjunctival epithelia to understand different ocular surface staining patterns in dry eye …