[HTML][HTML] Chaperones directly and efficiently disperse stress-triggered biomolecular condensates
Stresses such as heat shock trigger the formation of protein aggregates and the induction of
a disaggregation system composed of molecular chaperones. Recent work reveals that …
a disaggregation system composed of molecular chaperones. Recent work reveals that …
The inner workings of an ancient biological clock
Circadian clocks evolved in diverse organisms as an adaptation to the daily swings in
ambient light and temperature that derive from Earth's rotation. These timing systems, based …
ambient light and temperature that derive from Earth's rotation. These timing systems, based …
Nutritional compensation of the circadian clock is a conserved process influenced by gene expression regulation and mRNA stability
CM Kelliher, EL Stevenson, JJ Loros, JC Dunlap - PLoS Biology, 2023 - journals.plos.org
Compensation is a defining principle of a true circadian clock, where its approximately 24-
hour period length is relatively unchanged across environmental conditions. Known …
hour period length is relatively unchanged across environmental conditions. Known …
Network switches and their role in circadian clocks
M Del Olmo, S Legewie, M Brunner, T Höfer… - Journal of Biological …, 2024 - ASBMB
Circadian rhythms are generated by complex interactions among genes and proteins. Self-
sustained∼ 24 h oscillations require negative feedback loops and sufficiently strong …
sustained∼ 24 h oscillations require negative feedback loops and sufficiently strong …
Statistical data retrieval technique in astronomy computational physics
Computational astronomy is a very important branch in today's era, where physicists or
researchers can use computers to process statistics in astronomical physics. researchers …
researchers can use computers to process statistics in astronomical physics. researchers …
KidA, a multi-PAS domain protein, tunes the period of the cyanobacterial circadian oscillator
SJ Kim, C Chi, G Pattanayak… - Proceedings of the …, 2022 - National Acad Sciences
The cyanobacterial clock presents a unique opportunity to understand the biochemical basis
of circadian rhythms. The core oscillator, composed of the KaiA, KaiB, and KaiC proteins …
of circadian rhythms. The core oscillator, composed of the KaiA, KaiB, and KaiC proteins …
Evolution of the repression mechanisms in circadian clocks
Background Circadian (daily) timekeeping is essential to the survival of many organisms. An
integral part of all circadian timekeeping systems is negative feedback between an activator …
integral part of all circadian timekeeping systems is negative feedback between an activator …
Shift in conformational equilibrium underlies the oscillatory phosphoryl transfer reaction in the circadian clock
Oscillatory phosphorylation/dephosphorylation can be commonly found in a biological
system as a means of signal transduction though its pivotal presence in the workings of …
system as a means of signal transduction though its pivotal presence in the workings of …
Multimeric structure enables the acceleration of KaiB-KaiC complex formation induced by ADP/ATP exchange inhibition
S Koda, S Saito - PLOS Computational Biology, 2022 - journals.plos.org
Circadian clocks tick a rhythm with a nearly 24-hour period in a variety of organisms. In the
clock proteins of cyanobacteria, KaiA, KaiB, and KaiC, known as a minimum circadian clock …
clock proteins of cyanobacteria, KaiA, KaiB, and KaiC, known as a minimum circadian clock …
A role for gene expression and mRNA stability in nutritional compensation of the circadian clock
CM Kelliher, EL Stevenson, JJ Loros, JC Dunlap - bioRxiv, 2022 - biorxiv.org
Compensation is a defining principle of a true circadian clock, where its approximately 24-
hour period length is relatively unchanged across environmental conditions. Known …
hour period length is relatively unchanged across environmental conditions. Known …