Malignant mesothelioma and its non-asbestos causes

RL Attanoos, A Churg… - … of pathology & …, 2018 - meridian.allenpress.com
Context.—Although many mesotheliomas are related to asbestos exposure, not all are, and
there is increasing information on other causes of mesothelioma. Objective.—To provide a …

[HTML][HTML] Application of immunohistochemistry in diagnosis and management of malignant mesothelioma

DB Chapel, JJ Schulte, AN Husain… - Translational lung cancer …, 2020 - ncbi.nlm.nih.gov
Immunohistochemistry plays an indispensable role in accurate diagnosis of malignant
mesothelioma, particularly in morphologically challenging cases and in biopsy and cytology …

MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural …

DB Chapel, JJ Schulte, K Berg, A Churg, S Dacic… - Modern …, 2020 - nature.com
Ancillary studies facilitate accurate diagnosis of morphologically challenging mesothelial
proliferations. The current diagnostic algorithm proceeds from BAP1 immunohistochemistry …

Advances in the management of peritoneal malignancies

V Kepenekian, A Bhatt, J Peron, M Alyami… - Nature Reviews …, 2022 - nature.com
Peritoneal surface malignancies (PSMs) are usually associated with a poor prognosis.
Nonetheless, in line with advances in the management of most abdominopelvic metastatic …

BAP1 haploinsufficiency predicts a distinct immunogenic class of malignant peritoneal mesothelioma

R Shrestha, N Nabavi, YY Lin, F Mo, S Anderson… - Genome medicine, 2019 - Springer
Abstract Background Malignant peritoneal mesothelioma (PeM) is a rare and fatal cancer
that originates from the peritoneal lining of the abdomen. Standard treatment of PeM is …

[HTML][HTML] Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42

M Stevers, JT Rabban, K Garg, J Van Ziffle, C Onodera… - Modern Pathology, 2019 - Elsevier
Well-differentiated papillary mesothelioma is an uncommon mesothelial neoplasm that most
frequently arises in the peritoneal cavity of women of reproductive age. Whereas malignant …

[HTML][HTML] Molecular characterization of peritoneal mesotheliomas

M Offin, SR Yang, J Egger, G Jayakumaran… - Journal of Thoracic …, 2022 - Elsevier
Abstract Introduction Malignant peritoneal mesothelioma (MPeM) is clinically distinct and
less studied than malignant pleural mesothelioma. We report the genomic and …

Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications

Y Fang, X Shen - Cancer and Metastasis Reviews, 2017 - Springer
Protein ubiquitination and deubiquitination participate in a number of biological processes,
including cell growth, differentiation, transcriptional regulation, and oncogenesis. Ubiquitin C …

Organoids derived from patients provide a new opportunity for research and individualized treatment of malignant peritoneal mesothelioma

XC Fang, L Shu, TL Chen, XL Zhao, LC Yang, T Dou… - Molecular Cancer, 2024 - Springer
Background Malignant peritoneal mesothelioma (MPM) is an extremely rare and highly
invasive tumor. Due to the lack of accurate models that reflect the biological characteristics …

Nuclear grading, BAP1, mesothelin and PD-L1 expression in malignant pleural mesothelioma: prognostic implications

F Forest, A Patoir, P Dal Col, A Sulaiman, F Camy… - Pathology, 2018 - Elsevier
For malignant pleural mesothelioma (MPM), histopathological subtype is one of the most
important prognostic factors. Several immunohistochemical stains whose expressions have …