Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …

Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …

Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …

The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Acidity-stimulated platforms have the potential to improve the specificity of cancer imaging
and therapy within the tumor microenvironment (pH 6.5–6.8). However, avoiding non …

Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …

In the last decade, the use of nanotheranostics as emerging diagnostic and therapeutic tools
for various diseases, especially cancer, is held great attention. Up to date, several …

Rationale: The present study reports the multifunctional anticancer activity against B16F10
melanoma cancer cells and the bioimaging ability of fluorescent nitrogen-phosphorous …

Cancer nanomedicines rely on the enhanced permeability and retention (EPR) effect for
efficient target site accumulation. The EPR effect, however, is highly heterogeneous among …