Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …

Ventilator-associated pneumonia (VAP) is a serious intensive care unit (ICU)-related
infection in mechanically ventilated patients that is frequent, as more than half of antibiotics …

Scope These ESCMID guidelines address the targeted antibiotic treatment of third-
generation cephalosporin-resistant Enterobacterales (3GCephRE) and carbapenem …

CAZ-AVI and meropenem-vaborbactam seem destined to become the backbone of target
therapy for high-risk patients with severe infections caused by susceptible CRE strains …

Objective Carbapenem-resistant Enterobacteriaceae (CRE) has become a significant public
health problem in the last decade. We aimed to explore the risk factors of mortality in …

Introduction Ventilator-associated pneumonia (VAP) may be a life threatening nosocomial
infection encountered in intensive care units. Currently the emergence of carbapenem …

Carbapenem-resistant Klebsiella pneumoniae (CRKP) remains a major clinical pathogen
and public health threat with few therapeutic options. The mobilome, resistome, methylome …

Ventilator-associated pneumonia (VAP) infection caused by carbapenem-resistant
Enterobacteriaceae (CRE) is becoming more prevalent, thus seriously affecting patient …

Purpose To investigate the synergistic and bactericidal effects of antimicrobial combinations
of any two of colistin, fosfomycin and tigecycline against the nine extended-spectrum β …

Although the combination of polymyxin and tigecycline is widely used in treating
carbapenem-resistant bacterial infections, the benefit of this combination is still uncertain. To …