[HTML][HTML] The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease
Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …
[HTML][HTML] Lymphatic vessel network structure and physiology
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …
which has the holistic function to maintain the local physiologic environment for every cell in …
Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation
Background Genetic mutations drive the pathogenesis of the myelodysplastic syndrome
(MDS) and are closely associated with clinical phenotype. Therefore, genetic mutations may …
(MDS) and are closely associated with clinical phenotype. Therefore, genetic mutations may …
Lymphatic malformations: genetics, mechanisms and therapeutic strategies
Lymphatic vessels maintain tissue fluid homeostasis by returning to blood circulation
interstitial fluid that has extravasated from the blood capillaries. They provide a trafficking …
interstitial fluid that has extravasated from the blood capillaries. They provide a trafficking …
The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia
AS Sperling, CJ Gibson, BL Ebert - Nature Reviews Cancer, 2017 - nature.com
Myelodysplastic syndrome (MDS) is a clonal disease that arises from the expansion of
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
Primary lymphoedema
P Brouillard, MH Witte, RP Erickson… - Nature reviews Disease …, 2021 - nature.com
Lymphoedema is the swelling of one or several parts of the body owing to lymph
accumulation in the extracellular space. It is often chronic, worsens if untreated, predisposes …
accumulation in the extracellular space. It is often chronic, worsens if untreated, predisposes …
Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents
MW Wlodarski, S Hirabayashi, V Pastor… - Blood, The Journal …, 2016 - ashpublications.org
Germline GATA2 mutations cause cellular deficiencies with high propensity for myeloid
disease. We investigated 426 children and adolescents with primary myelodysplastic …
disease. We investigated 426 children and adolescents with primary myelodysplastic …
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia
Chromosomal rearrangements without gene fusions have been implicated in
leukemogenesis by causing deregulation of proto-oncogenes via relocation of cryptic …
leukemogenesis by causing deregulation of proto-oncogenes via relocation of cryptic …
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity
MA Spinner, LA Sanchez, AP Hsu… - Blood, The Journal …, 2014 - ashpublications.org
Haploinsufficiency of the hematopoietic transcription factor GATA2 underlies monocytopenia
and mycobacterial infections; dendritic cell, monocyte, B, and natural killer (NK) lymphoid …
and mycobacterial infections; dendritic cell, monocyte, B, and natural killer (NK) lymphoid …
Lymphatic system in cardiovascular medicine
The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …