Physiologically composed balanced isotonic electrolyte solutions are beneficial for
maintaining homeostasis, shifting the status more towards the normal range in patients with …

Background Iatrogenic hyponatremia is a common complication following intravenous
maintenance fluid therapy (IV-MFT) in hospitalized children. Despite the American Academy …

Importance The use of isotonic fluid therapy is currently recommended in children, but there
is limited evidence of optimal fluid therapy in acutely ill children. Objective To evaluate the …

Central diabetes insipidus (CDI) is a complex disorder in which large volumes of dilute urine
are excreted due to arginine-vasopressin deficiency, and it is caused by a variety of …

Importance Most children admitted to pediatric intensive care units (PICUs) receive
intravenous fluids. A recent systematic review suggested mortality benefit in critically ill …

Background: Respiratory syncytial virus (RSV) represents a global health challenge,
especially among younger children. While the disease burden in Japan has been …

1 Feldheiser A, Gelman S, Chew M, et al. Vasopressor effects on venous return in septic
patients: a review. Eur J Anaesthesiol 2021; 38: 659–663. 2 Brengelmann GL. Venous …

Background Fifty percent of patients with typical diarrhea-associated hemolytic uremic
syndrome (D+ HUS) require kidney replacement therapy (KRT). In these patients …

Over the last decade, our understanding of the impact of acute kidney injury and disorders of
fluid balance on outcomes in children across disease processes and age spectrum has …

Background. Fontan operation is a palliative medical procedure performed on children with
single‐ventricle defects. As postoperative success of the procedure largely depends on the …