[HTML][HTML] Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative …

S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …

[HTML][HTML] Mesenchymal stem cells and immunomodulation: current status and future prospects

F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …

[HTML][HTML] Mesenchymal stromal cell apoptosis is required for their therapeutic function

SHM Pang, J D'Rozario, S Mendonca, T Bhuvan… - Nature …, 2021 - nature.com
Multipotent mesenchymal stromal cells (MSCs) ameliorate a wide range of diseases in
preclinical models, but the lack of clarity around their mechanisms of action has impeded …

[HTML][HTML] Mesenchymal stem cells: a new trend for cell therapy

X Wei, X Yang, Z Han, F Qu, L Shao… - Acta Pharmacologica …, 2013 - nature.com
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in
the clinic for approximately 10 years. From animal models to clinical trials, MSCs have …

[HTML][HTML] Differences and similarities between cancer and somatic stem cells: therapeutic implications

F Rossi, H Noren, R Jove, V Beljanski… - Stem cell research & …, 2020 - Springer
Over the last decades, the cancer survival rate has increased due to personalized therapies,
the discovery of targeted therapeutics and novel biological agents, and the application of …

Mechanisms of mesenchymal stromal cell immunomodulation

K English - Immunology and cell biology, 2013 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …

The potential of mesenchymal stem cell therapy for chronic lung disease

FF Cruz, PRM Rocco - Expert Review of Respiratory Medicine, 2020 - Taylor & Francis
Introduction: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung
function and survival in chronic inflammatory lung diseases, including asthma, chronic …

A placebo-controlled, randomized trial of mesenchymal stem cells in COPD

DJ Weiss, R Casaburi, R Flannery, M LeRoux-Williams… - Chest, 2013 - Elsevier
Background COPD is a devastating disease affecting millions worldwide. As disease
pathogenesis includes both chronic pulmonary and systemic inflammation, antiinflammatory …

Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic …

FF Cruz, ZD Borg, M Goodwin… - Stem cells …, 2015 - academic.oup.com
An increasing number of studies demonstrate that administration of either conditioned media
(CM) or extracellular vesicles (EVs) released by mesenchymal stromal cells (MSCs) derived …

Concise review: mesenchymal stem cells and translational medicine: emerging issues

G Ren, X Chen, F Dong, W Li, X Ren… - Stem cells …, 2012 - academic.oup.com
Mesenchymal stem cells (MSCs) are emerging as a promising therapeutic approach of cell-
based therapy for a wide range of autoimmune disorders and degenerative diseases. In …