Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …

Alzheimer's disease (AD) was used to describe pre-senile dementia to differentiate it from
senile dementia, which develops in the adult age group of more than 65 years. AD is …

Nearly 30% of adults 40 years and older in the United States are on a statin. Their
widespread use heightens the importance of careful consideration of their varied effects on …

Introduction: For half a century, a high level of total cholesterol (TC) or low-density
lipoprotein cholesterol (LDL-C) has been considered to be the major cause of …

Background This is an update of a Cochrane review first published in 2001. At that stage
there was insufficient evidence to recommend statins for the prevention of Alzheimer's …

ABSTRACT BACKGROUND In 2012, the United States Food and Drug Administration (FDA)
issued a warning regarding potential adverse effects of HMG-CoA reductase inhibitors …

Background: Despite the US Food and Drug Administration (FDA) warning regarding
cognitive impairment, the relationship between statins and cognition remains unknown …

Vascular dementia (VaD) is the second commonest cause of dementia. Stroke is the leading
cause of disability in adults in developed countries, the second major cause of dementia and …

Objective To evaluate the effect of statins on short-term cognitive function and the long-term
incidence of dementia. Patients and Methods A systematic search was performed of …