Cancer progression is a multifaceted process that entails several stages and demands the
persistent expression or activation of transcription factors (TFs) to facilitate growth and …

Disruption of the epigenetic program of gene expression is a hallmark of cancer that initiates
and propagates tumorigenesis. Altered DNA methylation, histone modifications and ncRNAs …

Thyroid cancer remains the most prevailing endocrine malignancy, and a progressively
increasing incidence rate has been observed in recent years, with 95% of thyroid cancer …

Cancer is an important factor threatening human life and health; in recent years, its morbidity
and mortality remain high and demosntrate an upward trend. It is of great significance to …

Background Risk stratification and personalized care are crucial in managing osteosarcoma
due to its complexity and heterogeneity. However, current prognostic prediction using …

The global incidence of thyroid cancer has increased over recent decades. Papillary thyroid
cancer (PTC) is the most common type of thyroid cancer and accounts for nearly 90% of all …

Bone cancer pain (BCP) affects~ 70% of patients in advanced stages, primarily due to bone
metastasis, presenting a substantial therapeutic challenge. Here, we profile orphan G …

Epithelial–mesenchymal transition (EMT) plays essential roles in promoting malignant
transformation of epithelial cells, leading to cancer progression and metastasis. During EMT …

Thyroid cancer is a common malignancy of the endocrine system, with papillary thyroid
cancer (PTC) being the most common type of pathology. The incidence of PTC is increasing …

Oral squamous cell carcinoma (OSCC) is the leading cause of death in patients with head
and neck cancer. Reliable biomarkers to guide treatment decisions for OSCC remain scarce …