Camptothecin, over four decades of surprising findings

A Lorence, CL Nessler - Phytochemistry, 2004 - Elsevier
Camptothecin (CPT) is a modified monoterpene indole alkaloid produced by Camptotheca
acuminata (Nyssaceae), Nothapodytes foetida, Pyrenacantha klaineana, Merrilliodendron …

[HTML][HTML] Manipulating indole alkaloid production by Catharanthus roseus cell cultures in bioreactors: from biochemical processing to metabolic engineering

J Zhao, R Verpoorte - Phytochemistry Reviews, 2007 - Springer
Catharanthus roseus plants produce many pharmaceutically important indole alkaloids, of
which the bisindole alkaloids vinblastine and vincristine are antineoplastic medicines and …

Plant cell cultures-an alternative and efficient source for the production of biologically important secondary metabolites

V Mulabagal, HS Tsay - International journal of applied science and …, 2004 - gigvvy.com
Plant cell culture systems represent a potential renewable source of valuable medicinal
compounds, flavors, fragrances, and colorants, which cannot be produced by microbial cells …

Contribution à l'étude photochimique de quelques plantes médicinales antidiabétiques de la ville de Bukavu et ses environs (Sud-Kivu, RD Congo).

MJD Mangambu, KF Mushagalusa… - Journal of Applied …, 2014 - ajol.info
Objectif: Cette étude avait pour but de réaliser un screening phytochimique de quelques
plantes médicinales utilisées pour-traiter le diabète par les tradipraticiens dans la ville de …

Producción de metabolitos secundarios de plantas mediante el cultivo in vitro

N Pérez-Alonso, E Jiménez - Biotecnología vegetal, 2011 - revista.ibp.co.cu
El cultivo in vitro de células y tejidos es una fuente alternativa para la producción de
valiosos compuestos activos a partir de plantas. El cultivo de células indiferenciadas ha sido …

Metabolic engineering of the indole pathway in Catharanthus roseus hairy roots and increased accumulation of tryptamine and serpentine

EH Hughes, SB Hong, SI Gibson, JV Shanks… - Metabolic …, 2004 - Elsevier
Transgenic hairy roots of Catharanthus roseus were established with glucocorticoid
inducible tryptophan decarboxylase (TDC) expression alone or in combination with …

[HTML][HTML] Produção de metabólitos secundários em cultura de células e tecidos de plantas: O exemplo dos gêneros Tabernaemontana e Aspidosperma

E Fumagali, RAC Gonçalves… - Revista Brasileira de …, 2008 - SciELO Brasil
Os estudos dos metabólitos secundários de plantas se desenvolveram aceleradamente nos
últimos 50 anos. Estes compostos são conhecidos por desempenharem um papel …

[HTML][HTML] Physiological and metabolic traits of Taxol biosynthesis of endophytic fungi inhabiting plants: plant-microbial crosstalk, and epigenetic regulators

NZ Mohamed, L Shaban, S Safan… - Microbiological Research, 2023 - Elsevier
Attenuating the Taxol productivity of fungi with the subculturing and storage under axenic
conditions is the challenge that halts the feasibility of fungi to be an industrial platform for …

A unique high-diversity natural product collection as a reservoir of new therapeutic leads

F Ghirga, D Quaglio, M Mori, S Cammarone… - Organic Chemistry …, 2021 - pubs.rsc.org
Plants represent a rich source of structurally diverse secondary metabolites, which can be
exploited in the development of new clinically important compounds. Indeed, due to their …

[HTML][HTML] Cardiotonic glycosides from biomass of Digitalis purpurea L. cultured in temporary immersion systems

N Pérez-Alonso, D Wilken, A Gerth, A Jähn… - Plant Cell, Tissue and …, 2009 - Springer
Cardiotonic glycosides are extracted mostly from leaves of Digitalis plants. Commercial
production of bioactive secondary metabolites by traditional agriculture is an inefficient …