Many RNA-binding proteins have modular structures and are composed of multiple repeats
of just a few basic domains that are arranged in various ways to satisfy their diverse …

The RNA recognition motif (RRM) is one of the most abundant protein domains in
eukaryotes. While the structure of this domain is well characterized by the packing of two α …

Most eukaryotic mRNA precursors (premRNAs) must undergo extensive processing,
including cleavage and polyadenylation at the 3′-end. Processing at the 3′-end is …

Specificity is key to biological regulation. Two families of RNA binding proteins,
heterogeneous nuclear ribonucleoproteins and serine-arginine–rich proteins, were initially …

The heterogeneous nuclear ribonucleoprotein (hnRNP) F belongs to the hnRNP H family
involved in the regulation of alternative splicing and polyadenylation and specifically …

As of March 2010, 141 structures of protein–RNA complexes with a molecular weight lower
than 40 kDa have been deposited in the Protein Data Bank (PDB). Of these structures, 52 …

Cleavage stimulation factor (CstF) is a heterotrimeric protein complex essential for
polyadenylation of mRNA precursors. The 77 kDa subunit, CstF-77, is known to mediate …

Down-regulated splicing factor SRSF3 is known to promote cellular senescence, an
important biological process in preventing cancer and contributing to individual aging, via its …

Novel and efficient strategies need to be developed to interfere with the SARS-CoV-2 virus.
One of the most promising pharmaceutical targets is the nucleocapsid protein (N) …

Abstract 'RNA recognition motifs (RRMs)'are common domain‐folds composed of 80–90
amino‐acid residues in eukaryotes, and have been identified in many cellular proteins. At …