Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife.

M Van den Berg, L Birnbaum, AT Bosveld… - Environmental …, 1998 - ehp.niehs.nih.gov
An expert meeting was organized by the World Health Organization (WHO) and held in
Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic …

Induction of cytochrome P450 as a biomarker for environmental contamination in aquatic ecosystems

TD Bucheli, K Fent - Critical reviews in environmental science and …, 1995 - Taylor & Francis
Representing toxicant‐induced changes in biological systems, biomarkers can serve as
linkers between contamination (cause) and biological effects, and therefore provide unique …

Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problems.

S Safe - Environmental health perspectives, 1993 - ehp.niehs.nih.gov
Polychlorinated biphenyls (PCBs) are industrial compounds that have been detected as
contaminants in almost every component of the global ecosystem including the air, water …

Chemical and toxicological characterizations of hydraulic fracturing flowback and produced water

Y He, SL Flynn, EJ Folkerts, Y Zhang, D Ruan… - Water research, 2017 - Elsevier
Hydraulic fracturing (HF) has emerged as a major method of unconventional oil and gas
recovery. The toxicity of hydraulic fracturing flowback and produced water (HF-FPW) has not …

Species-specific recombinant cell lines as bioassay systems for the detection of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-like chemicals

PM Garrison, K Tullis, J Aarts, A Brouwer… - … and Applied Toxicology, 1996 - Elsevier
Exposure to specific polychlorinated diaromatic hydrocarbons (PCDH), such as 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD, dioxin), produces a wide variety of species-and tissue …

Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance

J McKim, M James - Combinatorial chemistry & high throughput …, 2010 - ingentaconnect.com
One of the greatest challenges facing the pharmaceutical industry today is the failure of
promising new drug candidates due to unanticipated adverse effects discovered during …

Bioanalytical screening methods for dioxins and dioxin-like compounds—a review of bioassay/biomarker technology

PA Behnisch, K Hosoe, S Sakai - Environment International, 2001 - Elsevier
Determination of environmental pollutants utilizing biodetectors such as bioassays,
biomarkers, enzyme immunoassays (EIAs), or other bioanalytical tools is a continuously …

Derivation and application of relative potency estimates based on in vitro bioassay results

DL Villeneuve, AL Blankenship… - … and Chemistry: An …, 2000 - Wiley Online Library
Relative potency (REP) estimates are widely used to characterize and compare the potency
of a wide variety of samples analyzed using in vitro bioassays. Relative potency estimates …

Deformities in birds of the Great Lakes region

JP Giesy, JP Ludwig, DE Tillitt - Environmental science & …, 1994 - ACS Publications
DONALD E. TILLITT US Department of Interior Columbia, MO 65201 of human-
causedepisodes of toxicological effects in pop-ulations of wildlife species, only since World …

[图书][B] AMAP assessment report: Arctic pollution issues

A Monitoring - 1998 - oaarchive.arctic-council.org
A fully referenced, comprehensive scientific and technical report presenting the 1998 AMAP
assessment on the status of the Arctic environment with respect to pollution, including …