Toehold-mediated strand displacement (TMSD) reactions between double-stranded DNA
and single-stranded oligonucleotides, which use a toehold structure as a switch, enable …

Due to their unique properties, such as programmability, ligand-binding capability, and
flexibility, nucleic acids can serve as analytes and/or recognition elements for biosensing. To …

Fluctuation of nucleic acid expression and ultrasensitive and specific detection of these
variations in expression is a crucial subject in molecular medicine and clinical theranostics …

In recent years, DNA logic gates have been extensively applied in developing multiplex
processing platforms to provide an accurate decision on the diagnosis of multi-factor …

An ultrasensitive photoelectrochemical (PEC) biosensor was developed based on
cosensitization of biocompatible CuInS2/ZnS quantum dots (ZCIS QDs) and N-doped …

In this study, a novel colorimetric aptasensor was prepared by coupling trivalent peroxidase-
mimic DNAzyme and magnetic nanoparticles for highly sensitive and selective detection of …

Currently, PCR is the gold standard for the detection of hepatitis C virus (HCV). However, the
PCR technique is complicated and time-consuming, which prevents its application and …

It is critically important to detect antibiotic residues for monitoring food safety. In this study, an
enzyme-and label-free electrochemical aptasensor for antibiotics, with kanamycin (Kana) as …

The split G-quadruplex DNAzyme has emerged as a valuable tool for visual DNA detection.
Here, we successfully integrated colorimetric split G-quadruplex DNAzyme assay with …

MicroRNAs, essential for gene expression and physiological regulation, are considered to
be reliable biomarkers for the early diagnosis and treatment of cancers. Herein, a sensitive …