Rotavirus infection

SE Crawford, S Ramani, JE Tate… - Nature Reviews …, 2017 - nature.com
Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …

Rotaviruses: From pathogenesis to disease control—A critical review

CA Omatola, AO Olaniran - Viruses, 2022 - mdpi.com
Since their first recognition in human cases about four decades ago, rotaviruses have
remained the leading cause of acute severe dehydrating diarrhea among infants and young …

Viral gastroenteritis

TG Flynn, MP Olortegui, MN Kosek - The Lancet, 2024 - thelancet.com
Since the discovery of norovirus in 1972 as a cause of what was contemporarily known as
acute infectious non-bacterial gastroenteritis, scientific understanding of the viral …

Therapeutic potential of salicylamide derivatives for combating viral infections

J Xu, Y Xue, AA Bolinger, J Li, M Zhou… - Medicinal Research …, 2023 - Wiley Online Library
Since time immemorial human beings have constantly been fighting against viral infections.
The ongoing and devastating coronavirus disease 2019 pandemic represents one of the …

Diagnosis and management of gastrointestinal complications in adult cancer patients: 2017 updated evidence-based guidelines of the Infectious Diseases Working …

M Schmidt-Hieber, J Bierwirth, D Buchheidt… - Annals of …, 2018 - Springer
Cancer patients frequently suffer from gastrointestinal complications. In this manuscript, we
update our 2013 guideline on the diagnosis and management of gastrointestinal …

Advances in the development of antiviral compounds for rotavirus infections

MJ Tohmé, LR Delgui - MBio, 2021 - Am Soc Microbiol
Group A rotaviruses (RVAs) are the major cause of severe acute gastroenteritis (AGE) in
children under 5 years of age, annually resulting in nearly 130,000 deaths worldwide. Social …

Successful treatment of chronic norovirus gastroenteritis with nitazoxanide in a pediatric kidney transplant recipient

K Haubrich, S Gantt, T Blydt‐Hansen - Pediatric transplantation, 2018 - Wiley Online Library
Uncontrolled studies suggest a benefit of nitazoxanide for the treatment of norovirus
gastroenteritis in immunocompromised individuals. Here, we report the use of nitazoxanide …

Treading a HOSTile path: mapping the dynamic landscape of host cell–rotavirus interactions to explore novel host-directed curative dimensions

U Patra, U Mukhopadhyay, A Mukherjee, S Dutta… - Virulence, 2021 - Taylor & Francis
Viruses are intracellular pathogens and are dependent on host cellular resources to carry
out their cycles of perpetuation. Obtaining an integrative view of host–virus interaction is of …

Therapeutic potential of Nitazoxanide against Newcastle disease virus: a possible modulation of host cytokines

F Antony, Y Vashi, S Morla, H Mohan, S Kumar - Cytokine, 2020 - Elsevier
Newcastle disease (ND) is prevalent among the domesticated and the wild birds and is
caused by the avian paramyxovirus serotype-I (APMV-I). It is commonly known to affect …

[HTML][HTML] Activity of nitazoxanide against viral gastroenteritis: a systematic review

EM Tan, KA Cawcutt, CD Zomok, RS Go… - International Journal of …, 2017 - ijtmgh.com
Introduction: Nitazoxanide is an oral anti-parasitic agent that has been found to have broad
antiviral activity. Its role in the treatment of viral gastroenteritis is not well-studied. Given the …