The Na+-K+-ATPase (NKA) differs from most other ion transporters, not only in its capacity to
maintain a steep electrochemical gradient across the plasma membrane, but also as a …

Na, K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal
cells and vitally essential for their functions. A specialized functional diversity of the Na, K …

MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets
and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be …

Traumatic brain injury (TBI) leads to permanent neurological impairment, and methylene
blue (MB) exerts central nervous system neuroprotective effects. However, only one …

The number of neurofibrillary tangles containing abnormal hyperphosphorylated tau protein
correlates with the degree of dementia in Alzheimer's disease (AD). In addition …

There is a great need for treatment that arrests progression of chronic kidney disease.
Increased albumin in urine leads to apoptosis and fibrosis of podocytes and tubular cells …

Glutamate carboxypeptidase II (GCPII) is a transmembrane zinc metallopeptidase found
mainly in the nervous system, prostate and small intestine. In the nervous system, glia …

The ability of exogenous low ouabain concentrations to affect claudin expression and
therefore epithelial barrier properties was demonstrated previously in cultured cell studies …

Purpose Curcumin can regulate the polarization of microglia and alleviate traumatic brain
injury (TBI). However, its detailed action mechanism on downregulating Complement 1q-like …

The N-methyl-D-aspartate (NMDA) receptor plays an essential role in glutamatergic
transmission and synaptic plasticity and researchers are seeking for different modulators of …