Circuits and functions of the lateral habenula in health and in disease
H Hu, Y Cui, Y Yang - Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …
owing to new discoveries relating to its critical role in regulating negatively motivated …
Reward processing by the lateral habenula in normal and depressive behaviors
The brain reward circuit has a central role in reinforcing behaviors that are rewarding and
preventing behaviors that lead to punishment. Recent work has shown that the lateral …
preventing behaviors that lead to punishment. Recent work has shown that the lateral …
[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
Dysregulation of the lateral habenula in major depressive disorder
CA Browne, R Hammack, I Lucki - Frontiers in synaptic neuroscience, 2018 - frontiersin.org
Clinical and preclinical evidence implicates hyperexcitability of the lateral habenula (LHb) in
the development of psychiatric disorders including major depressive disorder (MDD). This …
the development of psychiatric disorders including major depressive disorder (MDD). This …
Activation of the lateral habenula‐ventral tegmental area neural circuit contributes to postoperative cognitive dysfunction in mice
Postoperative cognitive dysfunction (POCD) is common and is associated with poor
outcome. Neural circuit involvement in POCD is unknown. Lateral habenula (LHb) that …
outcome. Neural circuit involvement in POCD is unknown. Lateral habenula (LHb) that …
Habenular connections with the dopaminergic and serotonergic system and their role in stress‐related psychiatric disorders
The habenula (Hb) is a phylogenetically old epithalamic structure differentiated into two
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …
Lateral habenula beyond avoidance: Roles in stress, memory, and decision-making with implications for psychiatric disorders
PM Baker, V Mathis, L Lecourtier… - Frontiers in systems …, 2022 - frontiersin.org
In this Perspective review, we highlight some of the less explored aspects of lateral
habenula (LHb) function in contextual memory, sleep, and behavioral flexibility. We provide …
habenula (LHb) function in contextual memory, sleep, and behavioral flexibility. We provide …
The habenula in psychiatric disorders: more than three decades of translational investigation
M Fakhoury - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
The habenula is an epithalamic structure located at the center of the dorsal diencephalic
conduction system, a pathway involved in linking forebrain to midbrain regions. Composed …
conduction system, a pathway involved in linking forebrain to midbrain regions. Composed …
The lateral habenula and adaptive behaviors
SJY Mizumori, PM Baker - Trends in neurosciences, 2017 - cell.com
The evolutionarily conserved lateral habenula (LHb) enables dynamic responses to
continually changing contexts and environmental conditions. A model is proposed to …
continually changing contexts and environmental conditions. A model is proposed to …
Expression of mu opioid receptor in dorsal diencephalic conduction system: new insights for the medial habenula
The habenular complex, encompassing medial (MHb) and lateral (LHb) divisions, is a highly
conserved epithalamic structure involved in the dorsal diencephalic conduction system …
conserved epithalamic structure involved in the dorsal diencephalic conduction system …