Publisher Summary This chapter discusses the immune response to chemically induced,
transplantable tumors in syngeneic mice. It deals with those tumors that are immunogenic by …

Publisher Summary This chapter presents a framework of results showing that a host
bearing a progressive immunogenic tumor responds immunologically to its tumor by …

A major aim in immunology has been to understand how the immune system evokes
characteristic responses to infection, foreign tissue grafts and tumours. The current view of …

Materials and Methods Animals. 16-wk-old C57BL/6 mice were used in these experiments.
They were obtained from The Jackson Laboratory, Bar Harbor, ME. Tumors. FBL-3 (kindly …

The ability of noncytolytic Lyt-1+, 2-T cells immune to FBL-3 leukemia to effect eradication of
disseminated FBL-3 was studied. Adult thymectomized, irradiated, and T-depleted bone …

Neonatal thymectomy during the critical period, 2-4 d after birth, can induce various organ-
specific autoimmune diseases including oophoritis in A/J mice. The oophoritis thus induced …

In the present study we used an adoptive transfer model with athymic nude mice to
characterize the T cells involved in initiating and mediating skin allograft rejection. It was …

DA rats grafted with major histocompatibility complex-incompatible PVG heart grafts and
treated with cyclosporine (CY) for 10 d do not reject their grafts, and develop a state of …

A new method of cyclophosphamide (CP)-induced skin allograft tolerance in mice that can
regularly overcome fully allogeneic (major H-2 plus non-H-2) antigen barriers in mice has …

Adoptive immunotherapy is an approach to cancer treatment that has not received
significant evaluation in cancer patients. Recent developments in modern cellular …